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Breast milk from healthy women has higher anti- properties than women with vaginal infections during pregnancy. | LitMetric

AI Article Synopsis

Article Abstract

The aim of this study was to investigate the different immunological and antimicrobial properties of breast milk from women with (W) or without (WO) vaginal yeast infections during pregnancy in 85 lactating women (W, n = 43; WO, n = 42). Concentrations of IL-10, IgA, IgM, IgG, EGF, and TGF-α were similar in both groups. However, breast milk of women aged below 31 years old from the W-group showed higher concentration of EGF than the WO-group ( = 0.031). Breast milk from WO-group exhibited higher anti- properties than W-group, both via growth inhibition and aggregation of yeast cells ( < 0.001). Correlation analysis showed that breast milk concentration of TGF-α positively correlated with concentrations of IL-10 ( = 0.001) and IgA ( = 0.021) in the W-group. Data from our present study shows that although breast milk from women with vaginal infections during pregnancy may not sufficiently hinder growth, other immuno-modulatory bioactives may substitute for such a protective effect.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9992674PMC
http://dx.doi.org/10.1007/s10068-022-01088-xDOI Listing

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