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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9999134 | PMC |
| http://dx.doi.org/10.5847/wjem.j.1920-8642.2023.014 | DOI Listing |
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Xuebijing Injection Alleviates the Inflammatory Response in Patients with Venous-Arterial Extracorporeal Membrane Oxygenation: A Prospective Randomized Controlled Study.
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Background: Both acute myocardial infarction (AMI) and its salvage treatment, venoarterial-extracorporeal membrane oxygenation (VA-ECMO), may lead to the production of proinflammatory cytokines and further aggravate tissue damage. Xuebijing (XBJ) may modulate cytokine production involved in the inflammatory response. We aimed to determine the efficacy of XBJ in cardiogenic shock patients on VA-ECMO.
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Article Synopsis
- VA-ECMO techniques have advanced and are particularly beneficial for patients with reversible low cardiac output, such as the case of a 21-year-old male with congenital heart disease who experienced severe shock following an upper gastrointestinal bleed.
- Initial treatments included intubation, fluid resuscitation, and emergency endoscopy to control active bleeding, but the patient's condition worsened, leading to the need for VA-ECMO support due to severe ventricular dysfunction and high lactate levels.
- After optimizing care in the ICU and adjusting ventilation strategies, the patient's condition stabilized, allowing for extubation and the discontinuation of certain medications, reflecting a positive recovery trajectory.
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