AI Article Synopsis
- Lagos State has the highest COVID-19 burden in Nigeria, and a study assessed death factors among hospitalized patients there.
- Out of 2,858 patients, most were males (65.8%), young (average age 41.9), asymptomatic (55.5%), and had mild disease (73.8%); the overall death rate was 6.5%.
- Key risk factors for death included being male, older age, having comorbidities, and experiencing severe COVID-19, with males having a 50% higher chance and severely ill patients a 9-fold higher risk of death.
Article Abstract
Background: Lagos State has the highest burden of COVID-19 in Nigeria. We assessed associated factors with death from COVID-19 among hospitalized patients in Lagos, Nigeria.
Methods: A retrospective cross-sectional study was conducted using de-identified records of laboratory-confirmed COVID-19 patients admitted into 15 isolation centers in Lagos State between February 27, 2020, and September 30, 2020.
Results: A total of 2,858 COVID -19 patients were included in this study. The mean age of the patients was 41.9±15.5 years. A higher proportion of patients were males (65.8%), asymptomatic (55.5%), had no comorbid condition (72.2%) and had the mild disease (73.8%). The case fatality rate was 6.5%. The odds of death from COVID-19 infection increased by 4% with every increase in age (AOR 1.04, 95%CI 1.03-1.05, p<0.001). The chance of dying was 50% fold more among males (AOR 1.5, 95%CI 1.0 - 2.2, p = 0.042), 60% fold more among patients with comorbidity (AOR 1.6, 95%CI 1.3 - 2.4, p = 0.037) and 9 fold more among patients with severe COVID-19 infection (AOR 9.6, 95% CI 4.9 - 19.1, p <0.001).
Conclusion: The odds of dying was higher among males, the elderly, patients with comorbidity and severe COVID-19.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9993304 | PMC |
| http://dx.doi.org/10.4314/ahs.v22i3.52 | DOI Listing |
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