Introduction: Venous ulcers account for over 80% of chronic wounds in the lower extremities. Venous ulcers lead to a significant decrease in the patients' quality of life.
Aim: To compare the effectiveness of two different sub-bandage pressure values on healing and quality of life outcomes.
Material And Methods: The study included 116 outpatients with venous leg ulcers (VLUs), one group with a moderate compression pressure of 35-40 mm Hg and the second with a high pressure > 45 mm Hg. The Kaplan-Meier curve and log rank test were used to estimate healing by type of compression. Quality of life measures included: Quality of Life Index (QL), Numeric Pain Rating Scale (NPRS) and Geriatric Depression Scale (GDS). Patients were followed for 24 weeks.
Results: Kaplan-Maier analysis showed that a high pressure leads to a higher proportion of healed VLUs, compared to the moderate pressure ( = 0.011). QL, GDS and NPRS at the beginning were equalized between the groups. In patients with a high compression, there was a statistically significant increase in QL ( = 0.005), decrease in GDS ( = 0.040) and NPRS ( = 0.002) during 24 weeks. In patients with moderate compressions there was a statistically significant increase in QL ( = 0.013).
Conclusions: Patients who received high pressure, healed faster. When a high pressure was applied, there was a statistically significant increase in QL, decrease in GDS and NPRS compared to the group of patients to whom the moderate pressure was applied.
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http://dx.doi.org/10.5114/ada.2022.124709 | DOI Listing |
Orphanet J Rare Dis
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Department of Voice, Speech and Hearing Disorders, University Dysphagia Center, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Background: Bulbar function is frequently impaired in patients with spinal muscular atrophy (SMA). Although extremely important for the patient's quality of life, it is difficult to address therapeutically. Due to bulbar dysfunction, maximum mouth opening (MMO) is suspected to be reduced in children with SMA.
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Telethon Kids Institute, North Entrance Perth Children's Hospital, 15 Hospital Ave, Nedlands, WA, 6009, Australia.
Background: Urine is an attractive biospecimen for nutritional status and population health surveys. It is an excellent non-invasive alternative to blood for appropriate biomarkers in young children and is suitable for home-based collection, enabling representative collections across a population. However, the bulk of literature in this population is restricted to collection in primary care settings.
View Article and Find Full Text PDFBMC Res Notes
January 2025
Leibniz Institute for the Analysis of Biodiversity Change, Museum Koenig Bonn, Centre for Molecular Biodiversity Research, Bonn, Germany.
Objective: Fin clipping is the standard DNA sampling technique for whole genome sequencing (WGS) of small fish. The collection of fin clips requires anaesthesia or even euthanisation of the individual. Swabbing may be a less invasive, non-lethal alternative to fin-clipping.
View Article and Find Full Text PDFJ Nanobiotechnology
January 2025
School of Pharmacy, Monash University Malaysia, Jalan Lagoon Selatan, 47500, Bandar Sunway, Selangor, Malaysia.
Type 2 diabetes mellitus (T2DM) is a metabolic disorder characterized by insulin resistance, leading to elevated blood sugar levels. Exogenous insulin can counteract the diminished response to insulin and effectively controlling blood glucose levels, thereby minimizing diabetes-related complications. However, given the injectable nature of exogenous insulin, apprehensions regarding its safety and the difficulties associated with its administration have hindered its widespread and prompt utilization.
View Article and Find Full Text PDFBMC Nurs
January 2025
Department of Nursing, Jahrom University of Medical Sciences, Jahrom, Iran.
Background: Nursing care is important and necessary for Acute Coronary Syndrome patients who have undergone angiography and stenting, to minimize complications. The purpose of this study was to assess the effects of High-Quality Nursing Interventions on the quality of life and cardiac index of Acute Coronary Syndrome patients, treated with drug-eluting stents.
Methods: In this randomized trial, 70 patients of the cardiac intensive care units in one of Jahrom university of medical sciences hospitals (Iran) were selected from July 2023 to October 2023 by the available method, and randomly allocated (stochastic assignment) to two intervention (High-Quality Nursing Interventions) and control groups (routine nursing care).
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