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| http://dx.doi.org/10.1093/ehjcr/ytad033 | DOI Listing |
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The effect of transcutaneous auricular vagus nerve stimulation on cardiovascular function in subarachnoid hemorrhage patients: A randomized trial.
Elife
January 2025
Department of Neurosurgery, Washington University School of Medicine, Springfield, United States.
Background: Subarachnoid hemorrhage (SAH) is characterized by intense central inflammation, leading to substantial post-hemorrhagic complications such as vasospasm and delayed cerebral ischemia. Given the anti-inflammatory effect of transcutaneous auricular vagus nerve stimulation (taVNS) and its ability to promote brain plasticity, taVNS has emerged as a promising therapeutic option for SAH patients. However, the effects of taVNS on cardiovascular dynamics in critically ill patients, like those with SAH, have not yet been investigated.
View Article and Find Full Text PDFCardiotoxicity and peri-operative considerations in immune checkpoint inhibitor and chimeric antigen receptor T-cell therapy: a narrative review.
Anaesthesia
January 2025
Department of Cardiovascular Medicine, Department of Medicine, Lahey Hospital and Medical Center, Burlington, MA, USA.
Introduction: Immunotherapy has transformed cancer treatment, particularly with immune checkpoint inhibitors and chimeric antigen receptor T-cell therapy. Despite their efficacy, these therapies can induce cardiotoxicity, presenting significant clinical challenges. Immune checkpoint inhibitors can cause myocarditis; pericarditis; arrhythmias; and myocardial infarction through immune-mediated inflammation.
View Article and Find Full Text PDFThe Relationship Between the Kansas City Cardiomyopathy Questionnaire and Electrocardiographic Parameters in Predicting Outcomes After Cardiac Resynchronization Therapy.
Life (Basel)
November 2024
Department of Cardiology, Bagdasar-Arseni Emergency Hospital, Carol Davila University of Medicine and Pharmacy, 022328 Bucharest, Romania.
Background: Cardiac resynchronization therapy (CRT) is an essential treatment for patients with symptomatic heart failure and ventricular conduction abnormalities. Low-ejection-fraction (EF) cardiomyopathy often involves a wide QRS complex displaying a left bundle branch block (LBBB) morphology and markedly delayed activation of the LV lateral wall. Following CRT, patients with heart failure and LBBB have better outcomes and quality-of-life improvements.
View Article and Find Full Text PDFThe Role of Machine Learning in the Detection of Cardiac Fibrosis in Electrocardiograms: Scoping Review.
JMIR Cardio
December 2024
School of Biomedical Engineering, University of British Columbia, Vancouver, BC, Canada.
Background: Cardiovascular disease remains the leading cause of mortality worldwide. Cardiac fibrosis impacts the underlying pathophysiology of many cardiovascular diseases by altering structural integrity and impairing electrical conduction. Identifying cardiac fibrosis is essential for the prognosis and management of cardiovascular disease; however, current diagnostic methods face challenges due to invasiveness, cost, and inaccessibility.
View Article and Find Full Text PDFDesign and use of a Denoising Convolutional Autoencoder for reconstructing electrocardiogram signals at super resolution.
Artif Intell Med
December 2024
Department of Computer Science and Technology, Cambridge University, Cambridge, United Kingdom. Electronic address:
Electrocardiogram signals play a pivotal role in cardiovascular diagnostics, providing essential information on electrical hearth activity. However, inherent noise and limited resolution can hinder an accurate interpretation of the recordings. In this paper an advanced Denoising Convolutional Autoencoder designed to process electrocardiogram signals, generating super-resolution reconstructions is proposed; this is followed by in-depth analysis of the enhanced signals.
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