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A Rare Case of Pembrolizumab-Associated Graves' Disease. | LitMetric

A Rare Case of Pembrolizumab-Associated Graves' Disease.

Cureus

Internal Medicine, Northwell Health at Mather Hospital, Port Jefferson, USA.

Published: February 2023

Immune checkpoint inhibitors (ICPis), such as pembrolizumab (Keytruda®), are associated with the development of several immune-related adverse events (irAEs). Thyroid dysfunction is a common endocrine irAE associated with pembrolizumab; however, Graves' disease induced by pembrolizumab is extremely rare. Few cases of this condition have been reported in the literature. Here, we report the case of a 50-year-old patient who presented with thyrotoxicosis that was attributed to Graves' disease secondary to pembrolizumab therapy.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998112PMC
http://dx.doi.org/10.7759/cureus.34696DOI Listing

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