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A novel strategy for the protective effect of ginsenoside Rg1 against ovarian reserve decline by the PINK1 pathway.
Pharm Biol
December 2025
The Affiliated Hospital, Changchun University of Chinese Medicine, Changchun, China.
Context: The decline in ovarian reserve is a major concern in female reproductive health, often associated with oxidative stress and mitochondrial dysfunction. Although ginsenoside Rg1 is known to modulate mitophagy, its effectiveness in mitigating ovarian reserve decline remains unclear.
Objective: To investigate the role of ginsenoside Rg1 in promoting mitophagy to preserve ovarian reserve.
Investigation of Novel Aronia Bioactive Fraction-Alginic Acid Nanocomplex on the Enhanced Modulation of Neuroinflammation and Inhibition of Aβ Aggregation.
Pharmaceutics
December 2024
Department of Pharmacy, College of Pharmacy, Ajou University, Suwon 16499, Republic of Korea.
Background/objectives: Aronia extract or its active compounds, especially anthocyanin, have shown potential for Alzheimer's disease (AD)-related pathologies, including neuroinflammation, fibrillogenesis of amyloid beta (Aβ), and cognitive impairment. However, there was still concern about their structural instability in vivo and in vitro. To solve the instability of anthocyanins, we combined aronia bioactive factions (ABFs) and alginic acid via electrostatic molecular interactions and created an ABF-alginic acid nanocomplex (AANCP).
View Article and Find Full Text PDFThe Role of Naphthaleneacetic Acid and 1-Methylcyclopropene in Preventing Preharvest Berry Dropping in L.
Plants (Basel)
January 2025
Department of Agricultural, Forest and Food Sciences, Università degli Studi di Torino, 10095 Grugliasco, Italy.
Fruit dropping represents a concern in many fruit species, including L. This research investigated the role of two plant growth regulators (PGRs), naphthaleneacetic acid (NAA) and 1-methylcyclopropene (1-MCP), in mitigating preharvest berry dropping (PHBD) through affecting ethylene (ET) and auxin (AUX) metabolism and interactions, key hormones involved in abscission. The experiment was carried out on cv.
View Article and Find Full Text PDFFood Insecurity and Coping Mechanisms: Impact on Maternal Mental Health and Child Malnutrition.
Nutrients
January 2025
Nutrition Program, Department of Nutrition and Food Science, School of Arts and Sciences, Lebanese American University, Chouran Beirut, P.O. Box 13-5053, Beirut 1102 2801, Lebanon.
Background: Household food insecurity (HFI) is a serious public health concern in Lebanon. Adverse mental health issues have been reported among food insecure households in addition to physical and nutritional complications. Caregivers in food insecure families tend to adopt different coping mechanisms to mitigate the effects of food insecurity (FI) on their children.
View Article and Find Full Text PDFThe Relationship Between a Mediterranean Diet and Frailty in Older Adults: NHANES 2007-2017.
Nutrients
January 2025
Department of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Background: Frailty is a geriatric syndrome of significant public health concern that causes vulnerability to physiologic stressors and an increased risk of mortality and hospitalizations. Dietary intake and quality are contributing factors to the development of frailty. The Mediterranean diet is known to be one of the healthiest eating patterns with promising health impacts for prevention.
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