This research examined the characteristics of cold days and spells in Bangladesh using long-term averages (1971-2000) of maximum () and minimum temperatures () and their standard deviations (SD). Cold days and spells were calculated and their rate of change during the winter months (December-February) of 2000-2021 was quantified. In this research, a cold day was defined as when the daily maximum or minimum temperature is ≤-1.5 the standard deviations of the long-term daily average of maximum or minimum temperature and the daily average air temperature was equal to or below 17 °C. The results showed that the cold days were more in the west-northwestern regions and far less in the southern and southeastern regions. A gradual decrease in cold days and spells was found from the north and northwest towards the south and southeast. The highest number of cold spells (3.05 spells/year) was experienced in the northwest Rajshahi division and the lowest (1.70 spells/year) in the northeast Sylhet division. In general, the number of cold spells was found to be much higher in January than in the other two winter months. In the case of cold spell severity, Rangpur and Rajshahi divisions in the northwest experienced the highest number of extreme cold spells against the highest number of mild cold spells in the Barishal and Chattogram divisions in the south and southeast. While nine (out of twenty-nine) weather stations in the country showed significant trends in cold days in December, it was not significant on the seasonal scale. Adapting the proposed method would be useful in calculating cold days and spells to facilitate regional-focused mitigation and adaptation to minimize cold-related deaths.
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http://dx.doi.org/10.3390/s23052832 | DOI Listing |
Alzheimers Dement
December 2024
Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Background: Calcineurin, a protein involved in functions such as synaptic plasticity and neuronal survival, plays an important role in the pathophysiology of Alzheimer's disease. This study, randomized, investigated the effects of FK506 (FK), a calcineurin inhibitor, on the behavioral, histological, and biochemical alterations observed in models of neurotoxicity induced by NMDA or Aβ and in a transgenic model for AD, in addition to the organotypic culture model stimulated with NMDA.
Methods: This study involved models for AD to experiment injecting NMDA or Aβ1-42 into the hippocampus of male C57Bl/6 mice aged 8-12 weeks to induce a neurotoxicity model, treating double-transgenic APP/PS1 mice, expressing both mouse/human APP and mutant human PS1, with chronic FK506 for AD, in which, to enable NMDA or Aβ1-42 microinjections, another experiment including a stereotaxic surgery was performed on the C57Bl/6 mice.
Sci Rep
January 2025
Key Laboratory of Semi-Arid Climate Change, College of Atmospheric Sciences, Ministry of Education, Lanzhou University, Lanzhou, 730000, China.
The impact of O on the respiratory system is a significant global problem. Nevertheless, there is insufficient information about its impact on respiratory disorders in northeast China. In this study, we used a generalized additive model (GAM) to determine the correlation between O concentrations and respiratory deaths based on the daily meteorological data, pollutant concentrations, and respiratory deaths from 2014 to 2016 in Shenyang, a typical city in northeast China.
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January 2025
Nutrition Departement, Faculty of Para-Medical Sciences, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
This study investigated the antioxidant and antimicrobial properties, as well as the volatile compounds, of Lactobacillus bulgaricus (L. bulgaricus) postbiotics (at concentration of 150 and 300 mg/L) and their combination with chitosan coatings (0.5% and 1%) on sausage quality (with 100 ppm nitrite) during 40 days of cold storage.
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January 2025
Department of Neonatology, Zahedan University of Medical Sciences, Zahedan, Iran.
The growing fetus is very sensitive to environmental conditions. There is limited and conflicting evidence about the short-term effects of exposure to air pollutants on the pregnancy outcome. In this time-stratified case-crossover study, the effect of several air pollutants (i.
View Article and Find Full Text PDFEnviron Res
December 2024
School of Public Health, Mongolian National University of Medical Sciences, Ulaanbaatar, 14210, Mongolia. Electronic address:
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