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Bayesian inference in epidemics: linear noise analysis. | LitMetric

Bayesian inference in epidemics: linear noise analysis.

Math Biosci Eng

Division of Scientific Computing, Department of Information Technology, Uppsala University, SE-751 05 Uppsala, Sweden.

Published: January 2023

This paper offers a qualitative insight into the convergence of Bayesian parameter inference in a setup which mimics the modeling of the spread of a disease with associated disease measurements. Specifically, we are interested in the Bayesian model's convergence with increasing amounts of data under measurement limitations. Depending on how weakly informative the disease measurements are, we offer a kind of 'best case' as well as a 'worst case' analysis where, in the former case, we assume that the prevalence is directly accessible, while in the latter that only a binary signal corresponding to a prevalence detection threshold is available. Both cases are studied under an assumed so-called linear noise approximation as to the true dynamics. Numerical experiments test the sharpness of our results when confronted with more realistic situations for which analytical results are unavailable.

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Source
http://dx.doi.org/10.3934/mbe.2023193DOI Listing

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