Inspired by the design criteria of heteroditopic receptors for ion-pair binding, we herein describe a new strategy to construct a rotaxane transporter (RR[2]) for K/Cl co-transport. The use of a rigid axle improves the transport activity with an EC value of 0.58 μM, presenting a significant step toward developing rotaxane artificial channels.
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| http://dx.doi.org/10.1039/d3cc00811h | DOI Listing |
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