The current study explored the slide-lengthening potentials of double and triple hemisections and the biomechanical effects of different inter-hemisection distances. Forty-eight porcine flexor digitorum profundus tendons were divided into double- and triple-hemisection groups (Groups A and B) and a control group (Group C). Group A was divided into Group A1 (distance between hemisections were the same as Group B) and Group A2 (distance between hemisections corresponded to the greatest distance between hemisections in Group B). Biomechanical evaluation, motion analysis, and finite element analysis (FEA) were performed. Failure load of intact tendon was significantly highest among groups. When the distance was 4 cm, the failure load of Group A increased significantly. When the distance between the hemisections was 0.5 or 1 cm, the failure load of Group B was significantly lower than Group A. Tendon elongation and failure load of Group B were significantly lower than those in Group A when the greatest distance between hemisections was the same. Consequently, Double hemisections had a similar lengthening ability to that of triple hemisections with the same distance, but better when the distances between extreme hemisections matched. However, the driving force for the initiation of lengthening may be greater.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998391 | PMC |
| http://dx.doi.org/10.1038/s41598-023-30791-w | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Porcine Models of Spinal Cord Injury.
Biomedicines
August 2023
Center for Brain Injury & Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Large animal models of spinal cord injury may be useful tools in facilitating the development of translational therapies for spinal cord injury (SCI). Porcine models of SCI are of particular interest due to significant anatomic and physiologic similarities to humans. The similar size and functional organization of the porcine spinal cord, for instance, may facilitate more accurate evaluation of axonal regeneration across long distances that more closely resemble the realities of clinical SCI.
View Article and Find Full Text PDFSpinal control of locomotion before and after spinal cord injury.
Exp Neurol
October 2023
Department of Neurological Surgery, University of Louisville School of Medicine, Health Sciences Campus, Louisville, KY, USA; Kentucky Spinal Cord Injury Research Center, University of Louisville School of Medicine, Health Sciences Campus, Louisville, KY, USA.
Thoracic spinal cord injury affects long propriospinal neurons that interconnect the cervical and lumbar enlargements. These neurons are crucial for coordinating forelimb and hindlimb locomotor movements in a speed-dependent manner. However, recovery from spinal cord injury is usually studied over a very limited range of speeds that may not fully expose circuitry dysfunction.
View Article and Find Full Text PDFSpinal control of locomotion before and after spinal cord injury.
bioRxiv
June 2023
Department of Neurological Surgery, University of Louisville School of Medicine, Health Sciences Campus, Louisville, Kentucky, USA.
Article Synopsis
- Thoracic spinal cord injury disrupts long propriospinal neurons that are essential for coordinating front and back limb movements during walking and running.
- Traditional recovery studies often focus on limited speeds, but this research explored overground locomotion in rats over a wider range of speeds before and after spinal cord injuries.
- Results showed that after injury, rats could still move at various speeds but lost high-speed gaits and exhibited altered limb coordination, underscoring the importance of speed diversity in understanding locomotor control and recovery post-injury.
A pilot study on lengthening potentials and biomechanical effects of double and triple hemisection on tendon with slide lengthening.
Sci Rep
March 2023
School of Mechanical Engineering, Shenyang University Of Technology, Shenyang, China.
The current study explored the slide-lengthening potentials of double and triple hemisections and the biomechanical effects of different inter-hemisection distances. Forty-eight porcine flexor digitorum profundus tendons were divided into double- and triple-hemisection groups (Groups A and B) and a control group (Group C). Group A was divided into Group A1 (distance between hemisections were the same as Group B) and Group A2 (distance between hemisections corresponded to the greatest distance between hemisections in Group B).
View Article and Find Full Text PDFMicrosurgical anatomy of the anterior cerebral artery and the arterial supply of the cingulate gyrus.
Surg Radiol Anat
April 2023
Department of Neurosurgery, School of Medicine, Ankara University, Ankara, Turkey.
Purpose: The cingulate gyrus is a potential surgical area to treat tumours, psychiatric diseases, intractable pain and vascular malformations. The aim of the study was to define the topographic anatomy and arterial supply of the cingulate gyrus located on the medial surface of the cerebral hemisphere.
Methods: We studied thirty-six hemispheres, each hemisected in the midsagittal plane.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!