Combined targeting of CCL7 and Flt3L to promote the expansion and infiltration of cDC1s in tumors enhances T-cell activation and anti-PD-1 therapy effectiveness in NSCLC.

Hong-Peng Dong Ying Li Zhen Tang Peng Wang Bo Zhong Qian Chu Dandan Lin

Cell Mol Immunol

Cancer Center, Renmin Hospital of Wuhan University, Medical Research Institute and Frontier Science Center of Immunology and Metabolism, Wuhan University, Wuhan, 430071, China.

Published: July 2023

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10310796	PMC
http://dx.doi.org/10.1038/s41423-023-00991-5	DOI Listing

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Combined targeting of CCL7 and Flt3L to promote the expansion and infiltration of cDC1s in tumors enhances T-cell activation and anti-PD-1 therapy effectiveness in NSCLC.

Download full-text PDF

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Similar Publications

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