Panuveitis by Coinfection with and Epstein Barr Virus. Should We Use Antiviral Therapy? - A Case Report.

Background: To report the atypical presentation and treatment in a case of and () intraocular coinfection.

Case Presentation: A 60-year-old male patient who presented anterior hypertensive uveitis followed by a new finding of a yellowish-white fluffy retinochoroidal lesion in the superior-temporal quadrant. He was initially treated with antiviral therapy without improvement. Next, due to the infection suspicion, anti-toxoplasmic treatment was added, and therapeutic and diagnostic vitrectomy was performed along with intravitreal clindamycin. Polymerase chain reaction (PCR) analysis in intraocular fluids confirmed and coinfection. Then, anti- oral treatment and antiviral and oral corticosteroids were administrated, achieving improvement.

Conclusions: In a patient with atypical retinochoroidal lesions, an intraocular fluids PCR should be performed, in addition to the serological laboratories to rule out coinfection, confirm the diagnosis, and establish an appropriate treatment. Coinfection could impact the pathogenesis and prognosis of the disease. OT: Ocular toxoplasmosis; ; EBV: ; CMV: Cytomegalovirus; HIV: Human Immunodeficiency Virus; HSV: ; VZV: ; PCR: Polymerase chain reaction; OD: Right eye; OS: Left eye; BCVA: best-corrected visual acuity.