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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9986751 | PMC |
| http://dx.doi.org/10.1183/23120541.00546-2022 | DOI Listing |
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Lupus mastitis is a presentation of lupus panniculitis that involves subcutaneous fat in patients with systemic lupus erythematosus (SLE). Moreover, lupus mastitis is a rare condition that typically presents as a palpable breast mass. Here, we report the case of a 29-year-old woman with a prior diagnosis of SLE who presented with palpable lumps in both breasts.
View Article and Find Full Text PDFChronic Leg Ulcerations and Subcutaneous Panniculitis due to Dermal Herpes Zoster in an Immunosuppressed Woman.
J Cutan Pathol
February 2025
Joan C. Edwards School of Medicine, Marshall University, Huntington, West Virginia, USA.
Herpes zoster (HZ) is a cutaneous viral disease that typically presents with a dermatomal vesicular eruption. Immunosuppressed patients are more likely to have atypical HZ involving chronic ulceration and disseminated distribution, making diagnosis a challenge. The current report describes a unique case of HZ in a woman with systemic lupus on immunosuppressive therapy manifesting as persistent lower extremity ulceration with diffuse dermal and endothelial infection and secondary panniculitis without epidermal involvement.
View Article and Find Full Text PDFErythema Nodosum Secondary to CD5-Positive Diffuse Large B-Cell Lymphoma as a Paraneoplastic Symptom: A Case Report.
Case Rep Oncol
September 2024
Department of Internal Medicine, Fukuyama City Hospital, Fukuyama, Japan.
Introduction: Erythema nodosum (EN) is the most common form of panniculitis. EN can be idiopathic or secondary to an underlying systemic disease, infection, drug use, or tumor. CD5-positive diffuse large B-cell lymphoma (CD5+ DLBCL) is a relapsed and refractory lymphoma, and further understanding of its pathology is required.
View Article and Find Full Text PDFBRAF/MEK inhibitors use for pediatric gliomas; real world experience from a resource-limited country.
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Department of Pediatrics, King Hussein Cancer Center, Amman, Jordan.
Introduction: Most pediatric low-grade-gliomas (LGG) and some high-grade-gliomas (HGG) have alterations in the RAS/MAPK pathway. Promising high tumor response rates were achieved using BRAF/MEK inhibitors, however data on their use in low-middle-income-countries (LMICs) are limited.
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A Retrospective Study of the Histopathological Spectrum of Erythema Nodosum Leprosum.
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August 2024
Department of Dermatology and Venereology, All India Institute of Medical Sciences, New Delhi, India.
Article Synopsis
- Recent studies on the histopathology of erythema nodosum leprosum (ENL) are lacking, which this research aims to address by describing its histopathological characteristics.
- A total of 125 biopsies were analyzed, revealing various infiltration patterns with the most common being a well-defined dermal infiltrate, observed in over half of the samples, along with varying degrees of subcutaneous tissue involvement.
- The findings highlighted the presence of immune cells like neutrophils and foamy histiocytes, with some cases showing acid-fast bacilli using specific staining techniques, although limitations included the retrospective nature of the study which hindered comparisons with clinical characteristics.
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