AI Article Synopsis

  • Gliosarcoma (GS) is a rare form of glioblastoma characterized by both glial and mesenchymal tissues, primarily found in cortical areas but occasionally in intraventricular spaces.
  • The report details a case of a 68-year-old woman with an uncommon intraventricular gliosarcoma (IVGS) originating from the left ventricle's frontal horn, which caused ventricular entrapment.
  • The study includes clinical information and tumor characteristics revealed through CT and MRI scans, as well as immunohistochemical analyses, alongside a review of other relevant literature.

Article Abstract

Gliosarcoma (GS) is an extraordinarily rare variant of glioblastoma, which is differentiated by its distinct biphasic histopathological morphology consisting of both glial and mesenchymal elements. Although GS has a predilection for the cortical hemispheres, rare occurrences of intraventricular gliosarcoma (IVGS) have been documented in the literature. In this report, we present a 68-year-old female patient with a primary IVGS arising from the frontal horn of the left ventricle with corresponding left ventricular entrapment. The clinical course as well as associated tumor features as observed on computed tomography (CT), magnetic resonance imaging (MRI), and immunohistochemical studies are presented along with a relevant review of the current literature.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9987255PMC
http://dx.doi.org/10.7759/cureus.34622DOI Listing

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