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Impact of Peridevice Leak Outcomes After Left Atrial Appendage Closure: Does Size No Longer Matter? | LitMetric

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http://dx.doi.org/10.1016/j.jacc.2022.08.815DOI Listing

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Impact of intensive versus nonintensive antithrombotic treatment on device-related thrombus after left atrial appendage closure.

Rev Esp Cardiol (Engl Ed)

December 2024

Institut Clínic Cardiovascular (ICCV), Hospital Clínic de Barcelona, Instituto de Investigaciones Biomédicas August Pi i Sunyer (IDIBAPS), Barcelona, Spain.

Introduction And Objectives: The optimal antithrombotic therapy (AT) after left atrial appendage closure (LAAC) is debated. We assessed the impact of intensive vs nonintensive AT on the incidence of device-related thrombus (DRT) based on whether the device implantation was classified as optimal or suboptimal.

Methods: This study included patients who underwent successful LAAC in 9 centers.

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Background: Research on the impact of angiographically detected residual trabeculation after left atrial appendage closure (LAAC) is limited.

Objectives: To investigate the incidence, characteristics, and clinical implications of angiographically detected residual trabeculation after LAAC using the WATCHMAN device.

Methods: We analyzed 1350 consecutive patients with atrial fibrillation undergoing LAAC using the WATCHMAN device from the OCEAN-LAAC registry, which is a prospective ongoing, multicenter Japanese registry.

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Background: The Amulet IDE trial (AMPLATZER Amulet Left Atrial Appendage Occluder [LAAO] Investigational Device Exemption [IDE] Trial) evaluated the safety and effectiveness of the Amulet occluder (Abbott) in patients with nonvalvular atrial fibrillation. The Amulet IDE trial is the largest randomized LAAO trial, comparing the Amulet occluder with the Watchman 2.5 device (Boston Scientific).

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Article Synopsis
  • Left atrial appendage occlusion (LAAO) procedures can be performed using either moderate sedation (MS) or general anesthesia (GA), and this study aimed to compare their effectiveness regarding lab time and complications.
  • The study included 135 patients and found that procedures under MS had significantly shorter total lab times (68.3 minutes) compared to GA (117.1 minutes), mainly due to reduced non-procedure time.
  • Despite the significant difference in lab time, there were no notable variations in complication rates or overall patient outcomes between the two anesthesia approaches.
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Prognostic Impact of Left Atrial Appendage Patency After Device Closure.

Circ Cardiovasc Interv

May 2024

Department of Cardiology, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, China.

Background: The prognostic impact of left atrial appendage (LAA) patency, including those with and without visible peri-device leak (PDL), post-LAA closure in patients with atrial fibrillation, remains elusive.

Methods: Patients with atrial fibrillation implanted with the WATCHMAN 2.5 device were prospectively enrolled.

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