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Composition and liquid-to-solid maturation of protein aggregates contribute to bacterial dormancy development and recovery.
Nat Commun
January 2025
Centre of Microbial and Plant Genetics, KU Leuven, Leuven, Belgium.
Recalcitrant bacterial infections can be caused by various types of dormant bacteria, including persisters and viable but nonculturable (VBNC) cells. Despite their clinical importance, we know fairly little about bacterial dormancy development and recovery. Previously, we established a correlation between protein aggregation and dormancy in Escherichia coli.
View Article and Find Full Text PDFDevelopment of PFAS-Free Locally Concentrated Ionic Liquid Electrolytes for High-Energy Lithium and Aluminum Metal Batteries.
Acc Chem Res
January 2025
Helmholtz Institute Ulm (HIU) Electrochemical Energy Storage, Helmholtzstrasse 11, 89081 Ulm, Germany.
ConspectusLithium-ion batteries (LIBs) based on graphite anodes are a widely used state-of-the-art battery technology, but their energy density is approaching theoretical limits, prompting interest in lithium-metal batteries (LMBs) that can achieve higher energy density. In addition, the limited availability of lithium reserves raises supply concerns; therefore, research on postlithium metal batteries is underway. A major issue with these metal anodes, including lithium, is dendritic formation and insufficient reversibility, which leads to safety risks due to short circuits and the use of flammable electrolytes.
View Article and Find Full Text PDFLimited reactivity of pyroxene and plagioclase in batch experiments with supercritical CO in the presence of NaCl and NaHCO in the context of CO sequestration via carbonation.
Environ Sci Pollut Res Int
January 2025
Council for Geoscience, Private Bag X112, Pretoria, 0001, South Africa.
One-step high-pressure and high-temperature direct aqueous mineral carbonation of tailings derived from mining of Platinum Group Metals in South Africa requires a fundamental understanding of the reactivity of the most dominant mineral phases, i.e. pyroxene and plagioclase (66 wt.
View Article and Find Full Text PDFGlycyrrhizinate Monoammonium Cysteine-Loaded Lipid Nanoparticles Allow for Improved Acute Liver Injury Therapy.
Pharmaceutics
January 2025
Department of Hepatobiliary Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Acute liver injury (ALI) is a prevalent and potentially lethal condition globally, where pharmacotherapy plays a vital role. However, challenges such as rapid drug excretion and insufficient concentration at hepatic lesions often impede the treatment's effectiveness. We successfully prepared glycyrrhizinate monoammonium cysteine (GMC)-loaded lipid nanoparticles (LNPs) using high-pressure homogenization.
View Article and Find Full Text PDFDirect Hot Solid-Liquid Extraction (DH-SLE): A High-Yield Greener Technique for Lipid Recovery from Coffee Beans.
Plants (Basel)
January 2025
Departamento de Química, Universidade Federal de Viçosa, Campus Universitário, Avenida Peter Henry Rolfs, s/n, Viçosa 36570-900, MG, Brazil.
Soxhlet extraction is a method recommended by the Association of Official Analytical Chemists (AOAC) to determine the lipid content in plant samples. Generally, n-hexane (toxicity grade 5) is used as the solvent (≈300 mL; ≈30 g sample) at boiling temperatures (69 °C) for long times (≤16 h) under a chilled water reflux (≈90 L/h), proportionally aggravated by the number of repetitions and samples determined. In this sense, the technique is neither safe nor sustainable for the analyst or the environment.
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