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| http://dx.doi.org/10.1164/rccm.202210-1898LE | DOI Listing |
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Studies on trematodes and acanthocephalans from freshwater fishes of Hubei Province, central China, with the erection of a new genus Quadrihexaspiron gen. n. (Acanthocephala: Neoechinorhynchidae).
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State Key Laboratory of Freshwater Ecology and Biotechnology, and Laboratory of Fish Diseases, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, Hubei Province, People's Republic of China *Address for correspondence: Frantisek Moravec, Institute of Parasitology, Biology Centre of the Czech Academy of Sciences, Branisovska 31, 370 05 Ceske Budejovice, Czech Republic. E-mail: ORCID: 0000-0003-1086-1181.
The present paper comprises a systematic survey of trematodes and acanthocephalans based on helminthological examinations of 64 specimens of 14 species of freshwater fishes, belonging to six families of four fish orders, mostly from localities in Hubei Province, central China, collected in the autumn of 2002. A total of 15 trematode species (in 12 families) and 5 acanthocephalan species (in four families) was recorded. Almost all parasites are briefly described and illustrated and problems concerning their morphology, taxonomy, hosts and geographical distribution are discussed.
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Circulating sexual stages of ) can be transmitted from humans to mosquitoes, thereby furthering the spread of malaria in the population. It is well established that antibodies can efficiently block parasite transmission. In search for naturally acquired antibodies targets on sexual stages, we established an efficient method for target-agnostic single B cell activation followed by high-throughput selection of human monoclonal antibodies (mAbs) reactive to sexual stages of in the form of gametes and gametocyte extracts.
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Infections caused by parasitic flatworms impart a significant disease burden. This is well exemplified by the neglected tropical disease schistosomiasis, which afflicts millions of people worldwide. The anti-schistosomal activity of various chemotypes has been known for decades, but the parasite targets of many of these remain undefined.
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