AI Article Synopsis
- A 27-year-old female with chronic active Epstein-Barr virus (EBV) infection achieved long-term remission through treatment with EBV-specific T cells and allogeneic hematopoietic stem cell transplantation (HSCT).
- The patient showed clearance of the virus following the use of anti-T-lymphocyte globulin, which was applied to prevent graft-versus-host disease (GvHD).
- Additionally, the growth of EBV-infected T cells was managed by administering transfusions of donor-derived EBV-specific T cells.
Article Abstract
We report sustained remission of chronic active Epstein-Barr virus (EBV) infection in a 27-year-old female patient treated with third-party EBV-specific T cells followed by allogeneic hematopoietic stem cell transplantation (HSCT). The viremia cleared after administration of anti-T-lymphocyte globulin for graft-versus-host disease (GvHD) prophylaxis. Subsequent expansion of EBV-infected host T cells was controlled by transfusion of donor-derived EBV-specific T cells.
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| http://dx.doi.org/10.1093/cid/ciad131 | DOI Listing |
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