Improving lateral resolution and contrast by combining coherent plane-wave compounding with adaptive weighting for medical ultrasound imaging.

Due to the severe lateral lobe artifact by coherent plane-wave compounding (CPWC) and the low signal-to-noise ratio of radiofrequency (RF) data collected from the plane wave, the adaptive beamforming methods based on focused wave imaging (FWI) are improper to be directly applied to CPWC. To obtain a high-quality image with high resolution and contrast, this study combined the threshold phase coherence factor (THR-PCF) with the reconstructed covariance matrix minimum variance (RCM-MV) and then proposed a novel CPWC-based adaptive beamforming algorithm, THR-PCF + RCM-MV. The simulation, phantom, and in-vivo experiments were performed to investigate the performance of the proposed methods in comparison with the CPWC and the classical adaptive methods including the minimum variance (MV), generalized coherence factor (GCF) and their combination GCF + MV. The simulation results demonstrated that the THR-PCF + RCM-MV beamformer improved contrast ratio (CR) by 28.14%, contrast noise ratio (CNR) by 22.01%, speckle signal-to-noise ratio (s_SNR) by 23.58%, generalized contrast-to-noise ratio (GCNR) by 0.3%, and the full width at half maximum (FWHM) by 43.38% on average, compared with the GCF + MV method. The phantom experimental results showed a better performance of the THR-PCF + RCM-MV beamformer with an average improvement by 21.95% in CR, 2.62% in s_SNR, and 48.64% in FWHM compared with the GCF + MV. Meanwhile, the results showed that the image quality of the near and far fields was enhanced by the THR-PCF + RCM-MV. The in-vivo imaging results showed that our new method had potential for clinical application. In conclusion, the lateral resolution and contrast of medical ultrasound imaging could be improved greatly with our proposed method.