Our perceptual system appears hardwired to exploit regularities of input features across space and time in seemingly stable environments. This can lead to serial dependence effects whereby recent perceptual representations bias current perception. Serial dependence has also been demonstrated for more abstract representations, such as perceptual confidence. Here, we ask whether temporal patterns in the generation of confidence judgments across trials generalize across observers and different cognitive domains. Data from the Confidence Database across perceptual, memory, and cognitive paradigms was reanalyzed. Machine learning classifiers were used to predict the confidence on the current trial based on the history of confidence judgments on the previous trials. Cross-observer and cross-domain decoding results showed that a model trained to predict confidence in the perceptual domain generalized across observers to predict confidence across the different cognitive domains. The recent history of confidence was the most critical factor. The history of accuracy or Type 1 reaction time alone, or in combination with confidence, did not improve the prediction of the current confidence. We also observed that confidence predictions generalized across correct and incorrect trials, indicating that serial dependence effects in confidence generation are uncoupled to metacognition (i.e., how we evaluate the precision of our own behavior). We discuss the ramifications of these findings for the ongoing debate on domain-generality versus domain-specificity of metacognition.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.3758/s13423-023-02261-x | DOI Listing |
iScience
February 2025
Department of Integrative Biology & Physiology, University of California, Los Angeles, Los Angeles, CA 90095, USA.
The vagus nerve is proposed to enable communication between the gut microbiome and the brain, but activity-based evidence is lacking. We find that mice reared germ-free exhibit decreased vagal tone relative to colonized controls, which is reversed via microbiota restoration. Perfusing antibiotics into the small intestines of conventional mice, but not germ-free mice, acutely decreases vagal activity which is restored upon re-perfusion with intestinal filtrates from conventional, but not germ-free, mice.
View Article and Find Full Text PDFMed Phys
January 2025
Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Background: Diffusing alpha-emitters Radiation Therapy ("Alpha DaRT") is a promising new radiation therapy modality for treating bulky tumors. Ra-carrying sources are inserted intratumorally, producing a therapeutic alpha-dose region with a total size of a few millimeter via the diffusive motion of Ra's alpha-emitting daughters. Clinical studies of Alpha DaRT have reported 100% positive response (30%-100% shrinkage within several weeks), with post-insertion swelling in close to half of the cases.
View Article and Find Full Text PDFbioRxiv
January 2025
Department of Chemistry, 409 McCormick Road, University of Virginia, Charlottesville, VA 22904.
Antibody production is central to protection against new pathogens and cancers, as well as to certain forms of autoimmunity. Antibodies often originate in the lymph node (LN), specifically at the extrafollicular border of B cell follicles, where T and B lymphocytes physically interact to drive B cell maturation into antibody-secreting plasmablasts. In vitro models of this process are sorely needed to predict aspects of the human immune response.
View Article and Find Full Text PDFMaterials (Basel)
January 2025
CITAB-Centre for the Research and Technology of Agro-Environmental and Biological Sciences, School of Science and Technology, University of Trás-os-Montes and Alto Douro, 5000-801 Vila Real, Portugal.
Epoxy resins are extensively employed as adhesives and matrices in fibre-reinforced composites. As polymers, they possess a viscoelastic nature and are prone to creep and stress relaxation even at room temperature. This phenomenon is also responsible for time-dependent failure or creep fracture due to cumulative strain.
View Article and Find Full Text PDFMicroorganisms
December 2024
Department of Biochemistry & Microbiology, Rutgers University, New Brunswick, NJ 08901, USA.
Breastfeeding supplies nutrition, immunity, and hormonal cues to infants. Feeding expressed breast milk may result in de-phased milk production and feeding times, which distort the real-time circadian cues carried by breast milk. We hypothesized that providing expressed breast milk alters the microbiotas of both breast milk and the infant's gut.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!