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Haematopoietic stem cell transplantation in children with inborn errors of immunity: A single centre experience.
Scand J Immunol
January 2025
Department of Pediatric Hematology Oncology & Bone Marrow Transplantation Unit, University of Health Sciences Ankara Bilkent City Hospital, Ankara, Turkey.
This study retrospectively analyzed the outcomes of 61 pediatric patients with inborn errors of immunity (IEI) who underwent hematopoietic stem cell transplantation (HSCT) between 2011 and 2023. Patients were categorized into primary immunodeficiency disorders (PIDD), primary immune dysregulation disorders (PIRD), and congenital defects of phagocyte number or function (CDP). Median ages at diagnosis and HSCT were 9 and 30 months, respectively.
View Article and Find Full Text PDFPrognostic factors in patients with localized and metastatic alveolar rhabdomyosarcoma. A report from two studies and two registries of the Cooperative Weichteilsarkom Studiengruppe CWS.
Cancer Med
January 2025
Department for Children and Adolescents, University Hospital Frankfurt, Goethe University, Frankfurt am Main, Germany.
Background: The histologic classification of rhabdomyosarcoma (RMS) as alveolar (aRMS) or embryonal (eRMS) is of prognostic importance, with the aRMS being associated with a worse outcome. Specific gene fusions (PAX3/7::FOXO1) found in the majority of aRMS have been recognized as markers associated with poor prognosis and are included in current risk stratification instead of histologic subtypes in localized disease. In metastatic disease, the independent prognostic significance of fusion status has not been definitively established.
View Article and Find Full Text PDFAdolescents' political and personal responses to recent policies restricting abortion and gender-affirming care.
Contracept X
December 2024
Department of Obstetrics and Gynecology, Section of Compex Family Planning, Ci3 at the University of Chicago, Chicago, IL, United States.
Objectives: Restrictive policies on abortion and gender-affirming care have increased in recent years, particularly in some Midwest states, and can have a disproportionate impact on young people. We sought to explore adolescent perspectives on such policies.
Study Design: We conducted virtual semistructured interviews with 39 participants aged 16 to 19 residing in the Midwest between April and June 2023, exploring participant reactions to state policies on abortion and gender-affirming care.
The relationship between temperament with nutritional status and anthropometric measurements in adult individuals.
J Nutr Sci
January 2025
Department of Nutrition and Dietetics, Faculty of Health Sciences, Gazi University, Ankara, Turkey.
Interest in studies examining the effect of temperament types on nutrition has recently increased. The aim of this study was to evaluate the relationship between nine types of temperament, anthropometric measurements, and nutrition in adults. This study was conducted on 1317 individuals aged between 18 and 55 years.
View Article and Find Full Text PDFWeight-neutral approach and later sleep midpoint in adolescents with "emerging polycystic ovary syndrome phenotype" as vehicles for sustainable weight loss.
F S Rep
December 2024
Departments of Neurology, Division of Sleep Medicine, and Obstetrics & Gynecology, Michigan Medicine, Ann Arbor, Michigan.
Objective: Incorporate sleep into a novel lifestyle intervention strategy in adolescents with Emerging symptoms of polycystic ovary syndrome (E-PCOS).
Design: A single-center cohort study.
Setting: University hospital-based clinic for adolescents with PCOS.
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