A Study to Evaluate the Effect of Opportunistic Salpingectomy on Ovarian Reserve and Function.

J Obstet Gynaecol India

Department of Obstetrics and Gynaecology, SGRRIHM&S and Shri Mahant Indiresh Hospital, Patel Nagar, Dehradun, Uttarakhand 248001 India.

Published: February 2023

AI Article Synopsis

  • A study was conducted to evaluate the impact of salpingectomy during hysterectomy on ovarian function in premenopausal women by measuring serum AMH and FSH levels before and after surgery.
  • The study involved 60 women and found that post-operative hormone levels were not significantly affected, regardless of whether salpingectomy was performed.
  • The conclusion was that salpingectomy, when done for benign reasons while preserving the ovaries, does not have negative short-term effects on ovarian reserve and function.

Article Abstract

Background: There are conflicting reports on status of ovarian function after hysterectomy and opportunistic salpingectomy in premenopausal women. The present study was undertaken to understand the effect of salpingectomy done at the time of hysterectomy on ovarian reserve and function as measured by serum AMH and FSH levels before and after the surgery.

Methods: This was a prospective study conducted on 60 women who underwent hysterectomy at our tertiary care centre, Shri Guru Ram Rai Institute of medical and health sciences, Dehradun, from January 2020 to September 2021. Serum AMH and FSH levels were monitored preoperatively and 3 months postoperatively in patients undergoing hysterectomy with bilateral salpingectomy and hysterectomy without salpingectomy.

Results: The mean age of the patients was 41.83 yrs in group 1 and 43.73 yrs in group 2 [ value = 0.078]. Most common indication of hysterectomy was AUB-L in both the groups (86% and 80%, respectively). Mean operative time was 115.50 min in group 1 and 114.40 min in group 2 [ value = 0.823]. Mean intra-operative blood loss was 214 ml in group 1 and 199.33 ml in group 2 [ value = 0.087]. Serum AMH and FSH were insignificantly decreased in both the groups post-operatively after 3 months, and the difference between both groups was also not statistically significant.

Conclusion: Salpingectomy done at the time of hysterectomy for benign indications with preservation of ovaries did not have any short-term adverse effects on ovarian reserve and function.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9984602PMC
http://dx.doi.org/10.1007/s13224-022-01709-9DOI Listing

Publication Analysis

Top Keywords

ovarian reserve
12
reserve function
12
serum amh
12
amh fsh
12
opportunistic salpingectomy
8
salpingectomy time
8
time hysterectomy
8
fsh levels
8
yrs group
8
hysterectomy
7

Similar Publications

Purpose: To investigate the follicle microenvironments of women with premature ovarian insufficiency (POI), with normal ovarian reserve function, and who are older (age >40 years) and to identify potential therapeutic targets.

Patients And Methods: In total, 9 women who underwent in vitro fertilization(IVF) or intracytoplasmic sperm injection(ICSI) were included in this study. The first punctured follicle of each patient was used.

View Article and Find Full Text PDF

Intrauterine adhesions (IUA) may lead to abnormal menstruation, infertility, and pregnancy-related complications. Hysteroscopic separation is the gold standard treatment for IUA and can be performed using a variety of instruments and methods, including cold scissors and electrotomy. However, it is unclear which method is more effective for relieving IUA, restoring uterine anatomy, and improving the pregnancy rate in women of childbearing age.

View Article and Find Full Text PDF

IL-33 and soluble ST2 in follicular fluid are associated with premature ovarian insufficiency.

Front Endocrinol (Lausanne)

December 2024

Department of Obstetrics and Gynecology, Center for Reproductive Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, China.

Background: Premature ovarian insufficiency (POI) is a common reproductive disease that is associated with chronic inflammation in ovaries. Interleukin 33 (IL-33) is a pro-inflammatory IL-1 family cytokine, and functions as an alarmin reflecting inflammatory reaction. Our study aimed to investigate levels of IL-33 and its soluble receptor (sST2) in both follicular fluid (FF) and paired serum during different stages of POI, and evaluate their predictive potentials for POI.

View Article and Find Full Text PDF

Given the significance of investigating ovarian reserve in infertile women, the limitations of existing diagnostic tests, and the absence of similar studies in this area, the present study aimed to examine the relationship between systemic inflammatory markers in patients with diminished ovarian reserve referred to the fertility clinic of Alzahra Hospital in Rasht in the year 2023. This cross-sectional analytical study was conducted on 174 patients referred to the Alzahra Hospital fertility clinic in Rasht. Patients were divided into two categories based on their serum levels of anti-Müllerian hormone (AMH):AMH >1.

View Article and Find Full Text PDF

Background: The ovarian response to gonadotropin stimulation varies widely among women, and could impact the probability of live birth as well as treatment risks. Many studies have evaluated the impact of different gonadotropin starting doses, mainly based on predictive variables like ovarian reserve tests (ORT) including anti-Müllerian hormone (AMH), antral follicle count (AFC), and basal follicle-stimulating hormone (bFSH). A Cochrane systematic review revealed that individualizing the gonadotropin starting dose does not affect efficacy in terms of ongoing pregnancy/live birth rates, but may reduce treatment risks such as the development of ovarian hyperstimulation syndrome (OHSS).

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!

A PHP Error was encountered

Severity: Notice

Message: fwrite(): Write of 34 bytes failed with errno=28 No space left on device

Filename: drivers/Session_files_driver.php

Line Number: 272

Backtrace:

A PHP Error was encountered

Severity: Warning

Message: session_write_close(): Failed to write session data using user defined save handler. (session.save_path: /var/lib/php/sessions)

Filename: Unknown

Line Number: 0

Backtrace: