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Polysaccharide-based hydrogel with photothermal effect for accelerating wound healing. | LitMetric

Polysaccharide-based hydrogel with photothermal effect for accelerating wound healing.

Carbohydr Polym

College of Chemical Engineering, Huaqiao University, Xiamen 361021, China.

Published: January 2023

AI Article Synopsis

  • Polysaccharide-based hydrogels have numerous advantages, such as excellent biochemical properties, good biocompatibility, and potential for use in biomedical applications, particularly wound healing.
  • Photothermal therapy (PTT) is a promising approach for preventing infections and enhancing wound healing, and when combined with polysaccharide-based hydrogels, it can lead to multifunctional treatments that are bactericidal and promote tissue regeneration.
  • This review outlines the principles of hydrogels and PTT, their applicable polysaccharides, design considerations for these hydrogels, and highlights current challenges and future prospects in this innovative field.

Article Abstract

Polysaccharide-based hydrogel has excellent biochemical function, abundant sources, good biocompatibility and other advantages, and has a broad application prospect in biomedical fields, especially in the field of wound healing. With its inherent high specificity and low invasive burden, photothermal therapy has shown great application prospect in preventing wound infection and promoting wound healing. Combining polysaccharide-based hydrogel with photothermal therapy (PTT), multifunctional hydrogel with photothermal, bactericidal, anti-inflammatory and tissue regeneration functions can be designed, so as to achieve better therapeutic effect. This review first focuses on the basic principles of hydrogel and PTT, and the types of polysaccharides that can be used to design hydrogels. In addition, according to the different materials that produce photothermal effects, the design considerations of several representative polysaccharide-based hydrogels are emphatically introduced. Finally, the challenges faced by polysaccharide-based hydrogels with photothermal properties are discussed, and the future prospects of this field are put forward.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.carbpol.2022.120228DOI Listing

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