In this report, we share the case of a 65-year-old male with a remote history of brain concussion who presented to the emergency department for evaluation of transient amnesia that lasted 30 minutes to one hour. He was found to have spontaneous intracerebral hemorrhage of the fornix as a cause of his amnesic episode. To date from the creation of this case report (January 2023), spontaneous hemorrhage of the fornix resulting in transient amnesia has not been previously described in the literature. The fornix is an unusual location for spontaneous hemorrhage to occur. The differential diagnosis of transient amnesia is broad and includes, but is not limited to, transient global amnesia, traumatic injury, hippocampal infraction, and various metabolic derangements. Determination of the etiology of transient amnesia can result in changes in treatment decisions. Because of this unique patient presentation, we propose that spontaneous hemorrhage of the fornix should be considered in patients who present with transient amnesia.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9981547PMC
http://dx.doi.org/10.7759/cureus.34519DOI Listing

Publication Analysis

Top Keywords

transient amnesia
20
hemorrhage fornix
16
spontaneous hemorrhage
12
case report
8
spontaneous intracerebral
8
intracerebral hemorrhage
8
amnesia
7
transient
6
spontaneous
5
hemorrhage
5

Similar Publications

Article Synopsis
  • The study investigates the role of the hippocampus (HPC) and amygdala in memory formation, particularly focusing on retrograde amnesia that occurs after HPC disruption.
  • Findings reveal that damage to the HPC does not affect conditioned place preference (CPP) tasks, which rely on the basolateral amygdala, suggesting that not all learning tasks require HPC involvement.
  • Additional experiments using the Morris water task indicate that while HPC damage impairs performance, other memory networks can't fully compensate when certain training methods are used, highlighting the complexity of memory processing.
View Article and Find Full Text PDF

The role of the medial part of the thalamus, and in particular the mediodorsal nucleus (MD) and the mammillothalamic tract (MTT), in memory has long been studied, but their contribution remains unclear. While the main functional hypothesis regarding the MTT focuses on memory, some authors postulate that the MD plays a supervisory executive role (indirectly affecting memory retrieval) due to its dense structural connectivity with the prefrontal cortex (PFC). Recently, it has been proposed that the MD, MTT and PFC form part of the DMN the default mode network (DMN).

View Article and Find Full Text PDF

Visual Exploration and the Primate Hippocampal Formation.

Hippocampus

January 2025

Department of Neurobiology and Biophysics, University of Washington School of Medicine, Washington National Primate Research Center, Seattle, Washington, USA.

During the 1990s and early 2000s, research in humans and in the nonhuman primate model of human amnesia revealed that tasks involving free viewing of images provided an exceptionally sensitive measure of recognition memory. Performance on these tasks was sensitive to damage restricted to the hippocampus as well as to damage that included medial temporal lobe cortices. Early work in my laboratory used free-viewing tasks to assess the neurophysiological correlates of recognition memory, and the use of naturalistic visual exploration opened rich avenues to assess other aspects of the impact of eye movements on neural activity in the hippocampus and entorhinal cortex.

View Article and Find Full Text PDF

Background: Transient global amnesia (TGA) is a benign neurological syndrome of unknown etiology, causing sudden anterograde amnesia that lasts up to 24 h. During the episode of TGA, other cognitive functions are normal. This is the first study describing the characteristics of the disease in Israel.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!