AI Article Synopsis
- The split preparation was created by treating the tick-borne encephalitis virus with a combination of Tween-80, ether, and formalin, successfully eliminating the active virus.
- After the detergent was removed, the resulting preparation still maintained its antigenic and immunogenic properties.
- This means it can still trigger an immune response without the risk of causing disease.
Article Abstract
The split preparation, obtained by the treatment of purified and concentrated tick-borne encephalitis virus with 0.5% Tween-80 and ether and inactivated with formalin at a minimal concentration of 1:10,000, did not contain the active virus. After the removal of the detergent, the preparation retained its antigenic and immunogenic properties.
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