Objective: () is an obligate intracellular protozoan and its definitive host is the Felidae family. Toxoplasmosis can be transmitted to humans in many ways. The purpose of the study was to investigate the anti- IgM and anti- IgG seropositivity with the ELISA method in people who have cats at home and do not have cats at home, and to reveal the possible relationship between toxoplasmosis and people who keep/contact cats for a long time for any reason at home.
Methods: Between March 2021 and June 2021, blood samples were taken from 91 people who had a cat in their home for at least a year and 91 people who had never had a cat or had no contact with a cat, in Sivas province. Anti- IgM and anti- IgG antibodies were investigated in serum samples by the ELISA method. Age, gender, and other socio-demographic criteria were not considered.
Resultsresults: Because of the study, all samples were found to be negative for anti- IgM. Anti- IgG seropositivity was detected in 20 (22.0%) of those who had cats at home and 40 (44.0%) of those without cats at home. There was no statistically significant difference between the two groups in terms of anti- IgM seropositivity. However, anti- IgG seropositivity was found to be statistically significant (p=0.002) (p<0.01).
Conclusion: Because of the study, anti- IgG positivity was found to be higher in those who did not feed/contact cats at home and it was statistically significant. It brings to mind that the reason for the high rate of seropositivity in those without cats at home, may not be only the oocysts excreted from cats, but also the transmission by other non-cat transmission routes may still be important.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.4274/tpd.galenos.2022.73745 | DOI Listing |
J Immunol Methods
January 2025
School of Biological Sciences, University of Aberdeen, Scotland, Zoology Building, Tillydrone Avenue, AB24 2TZ Aberdeen, Scotland, United Kingdom.
A novel panel of peptide for serological identification of Borrelia burgdoferi sensu stricto, Borrelia garinii and Borrelia afzelii was developed and assessed in this study. The diagnostic algorithm of the novel test was initially trained testing 10 US human sera including 3 early-stage and 3 late-stage Lyme disease positive sera, 2 sera positive for Babesia and 2 sera positive for Syphilis, all purchased from a private biorepository. Findings were then corroborated testing (a) 33 additional EU follow-up positive sera from seroconverted patients bitten by ticks that tested positive for B.
View Article and Find Full Text PDFViruses
December 2024
Faculty of Medicine, Federal University of Vale do São Francisco-UNIVASF, Petrolina 56304-917, PE, Brazil.
Arthropod-borne viral diseases are acute febrile illnesses, sometimes with chronic effects, that can be debilitating and even fatal worldwide, affecting particularly vulnerable populations. Indigenous communities face not only the burden of these acute febrile illnesses, but also the cardiovascular complications that are worsened by urbanization. A cross-sectional study was conducted in an Indigenous population in the Northeast Region of Brazil to explore the association between arboviral infections (dengue, chikungunya, and Zika) and cardiac biomarkers, including cardiotrophin 1, growth differentiation factor 15, lactate dehydrogenase B, fatty-acid-binding protein 3, myoglobin, N-terminal pro-B-type natriuretic peptide, cardiac troponin I, big endothelin 1, and creatine kinase-MB, along with clinical and anthropometric factors.
View Article and Find Full Text PDFInt Immunopharmacol
January 2025
AT-31 BIO Inc., 403 Business Incubation Center, Kyungpook National University, 80 Daehak-ro, Buk-gu, Daegu 41566, Republic of Korea; Laboratory of Immunobiology, School of Life Science and Biotechnology, College of Natural Sciences, Kyungpook National University, 80 Daehak-ro, Buk-gu, Daegu 41566, Republic of Korea. Electronic address:
Recombinant GH16B β-agarase-catalyzed liquefaction of 5-7 %(w/v) melted agarose at 50 °C completely hydrolyzed agarose into neoagarohexaose (NA6) and neoagarotetraose (NA4). Subsequent saccharification by recombinant GH50A β-agarase or recombinant GH50A β-agarase/recombinant GH117A α-neoagarobiose hydrolase at 35 °C converted NA6/NA4 into neoagarobiose (NA2) or 3,6-anhydro-L-galactose (L-AHG)/D-galactose, respectively. Purification of NA6/NA4 and NA2 was achieved by Sephadex G-15 column chromatography, while L-AHG was purified by Sephadex G-10, achieving ≥ 98 % purity.
View Article and Find Full Text PDFFront Immunol
December 2024
Center for Biomedical Network Research on Rare Diseases (CIBERER U767), Madrid, Spain.
Background: The use of next-generation sequencing in inborn errors of immunity (IEI) has considerably increased the identification of novel gene variants, many of which are identified in patients without the described clinical phenotype or with variants of uncertain pathogenic significance in previously described genes. Properly designed functional and cellular assays, many necessarily accomplished by research-based laboratories, reveal the pathogenic consequences of the gene variants and contribute to diagnosis. Activated PI3Kδ syndrome (APDS) is a rare disease that can be divided into APDS1, caused by gain of function (GOF) mutations in gene, and APDS2, with loss of function (LOF) variants in the gene.
View Article and Find Full Text PDFRev Med Inst Mex Seguro Soc
March 2024
Instituto Mexicano del Seguro Social. Centro Médico Nacional Siglo XXI, Hospital de Especialidades "Dr. Bernardo Sepúlveda", Servicio de Neurofisiología. Ciudad de México, México.
Background: Motor multifocal neuropathy is an immunemediated neuropathy characterized by progressive and asymmetric weakness of the distal extremities, without sensory symptoms, and an important feature of conduction blocks. The objective of this study is to comprehensively describe the nosological and pathogenic implications of this neurodegenerative disorder, given the unclear diagnosis of MMN and the significant challenges it poses.
Clinical Cases: We present three clinical cases with a chronic clinical presentation, in which neuroconduction studies were performed, revealing the presence of anti-IgM GM1 antibodies, consistent with the diagnosis of motor multifocal neuropathy.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!