AI Article Synopsis
- Chronic heart failure (CHF) is a serious and increasing health issue caused by various underlying heart diseases, leading to significant mortality and morbidity.
- Different conditions such as coronary heart disease, hypertension, diabetes, and cardiomyopathy can lead to CHF, highlighting the need for distinct animal models for research.
- The paper reviews the animal models developed over the last decade, emphasizing their role in studying CHF's causes and treatments, especially in the context of traditional Chinese medicine (TCM).
Article Abstract
Chronic heart failure(CHF) is a series of clinical syndromes in which various heart diseases progress to their end stage. Its morbidity and mortality are increasing year by year, which seriously threatens people's life and health. The diseases causing CHF are complex and varied, such as coronary heart disease, hypertension, diabetes, cardiomyopathy and so on. It is of great significance to establish animal models of CHF according to different etiologies to explore the pathogenesis of CHF and develop drugs to prevent and treat CHF induced by different diseases. Therefore, based on the classification of the etiology of CHF, this paper summarizes the animal models of CHF widely used in recent 10 years, and the application of these animal models in traditional Chinese medicine(TCM) research, in order to provide ideas and strategies for studying the pathogenesis and treatment of CHF, and provide ideas for TCM modernization research.
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| http://dx.doi.org/10.19540/j.cnki.cjcmm.20220918.201 | DOI Listing |
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