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Association Between Patient Characteristics and the Depth of Microvascular Penetration Into the Adult Human Meniscus.
Am J Sports Med
January 2025
Department of Orthopaedics, Isala Hospital, Zwolle, The Netherlands.
Background: Current knowledge on the microvascular anatomy of adult human menisci is based on cadaveric studies. However, considerable interindividual variation in meniscal microvascularization has been reported in recent studies with small sample sizes.
Purpose: To assess the association between patient characteristics and the depth of microvascularization of the meniscus.
Laboratory-Engineered Glioblastoma Organoid Culture and Drug Screening.
J Vis Exp
January 2025
Division of Molecular Neurogenetics, German Cancer Research Center (DKFZ);
Glioblastoma (GBM) is described as a group of highly malignant primary brain tumors and stands as one of the most lethal malignancies. The genetic and cellular characteristics of GBM have been a focal point of ongoing research, revealing that it is a group of heterogeneous diseases with variations in RNA expression, DNA methylation, or cellular composition. Despite the wealth of molecular data available, the lack of transferable pre-clinic models has limited the application of this information to disease classification rather than treatment stratification.
View Article and Find Full Text PDFPeroneus brevis split tear - A challenging diagnosis: A pictorial review of magnetic resonance and ultrasound imaging. Part 1. Anatomical basis and clinical insights.
Eur J Radiol Open
June 2025
Department of Radiology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Diagnosing peroneus brevis split tears is a significant challenge, as many cases are missed both clinically and on imaging. Anatomical variations within the superior peroneal tunnel can contribute to peroneus brevis split tears or instability of the peroneal tendons. However, determining which anatomical variations predispose patients to these injuries remains challenging due to conflicting data in the literature.
View Article and Find Full Text PDFTandem repeats are a highly polymorphic class of genomic variation that play causal roles in rare diseases but are notoriously difficult to sequence using short-read techniques . Most previous studies profiling tandem repeats genome-wide have reduced the description of each locus to the singular value of the length of the entire repetitive locus . Here we introduce a comprehensive database of 3.
View Article and Find Full Text PDFMethodological Approaches to Comparative Trend Analyses: The Case of Adolescent Toothbrushing.
Int J Public Health
January 2025
Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
Objectives: Research questions about how and why health trends differ between populations require decisions about data analytic procedure. The objective was to document and compare the information returned from stratified, fixed effect and random effect approaches to data modelling for two prototypical descriptive research questions about comparative trends in toothbrushing.
Methods: Data included five cycles of the Health Behaviour in School-aged Children 2006 to 2022, which provided a sample of 980192 11- to 15- year olds from 35 countries.
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