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Chlorin e6: a promising photosensitizer of anti-tumor and anti-inflammatory effects in PDT.
Nanomedicine (Lond)
January 2025
Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou, China.
Photodynamic therapy (PDT) involves the activation of photosensitizers (PSs) by visible laser light at the target site to catalyze the production of reactive oxygen species, resulting in tumor cell death and blood vessel closure. The efficacy of PDT depends on the PSs, the amount of oxygen, and the intensity of the excitation laser. PSs have been extensively researched, and great efforts have been made to develop an ideal photosensitizer.
View Article and Find Full Text PDFMode-selective converters (MSCs) play an indispensable role in mode division multiplexing (MDM) systems, and the commonly used cascaded waveguide-based MSCs not only have a relatively large size but also increase the insertion loss and mode crosstalk during the conversion process. In this paper, a parallel six-mode-selective converter (6-MSC) is proposed to enhance the integration of the device, which consists of a photonic crystal fiber (PCF) and six step-index fibers (SIFs). Here, a PCF without any holes in the cladding is proposed.
View Article and Find Full Text PDFThis paper demonstrates a customized quartz tuning fork (QTF) coated with the titanium carbide (TiCT) MXene film that can effectively enhance the sensitivity of light-induced thermoelastic spectroscopy (LITES). The MXene film is coated at the root of the customized QTF. The film area is proven to have little impact on resonance frequency, bandwidth, quality factor, and amplitude of the second harmonic signal (2) based on the fundamental flexural mode.
View Article and Find Full Text PDFPerovskites attract significant attention as a coating material in optical fiber sensing, but challenges remain due to the limited discovery of suitable materials and the high trial-and-error costs, resulting in only a few perovskites being used in optical sensing experiments. Addressing this issue, a novel systematic computational screening strategy for perovskites is established. This strategy is demonstrated to accelerate the discovery of perovskite coating materials that can enhance optical sensing sensitivity.
View Article and Find Full Text PDFBiphasic lipid extraction from microalgae after PEF-treatment reduces the energy demand of the downstream process.
Biotechnol Biofuels Bioprod
January 2025
Institute for Pulsed Power and Microwave Technology (IHM), Karlsruhe Institute of Technology (KIT), Eggenstein-Leopoldshafen, Germany.
Background: The gradual extrusion of water-soluble intracellular components (such as proteins) from microalgae after pulsed electric field (PEF) treatment is a well-documented phenomenon. This could be utilized in biorefinery applications with lipid extraction taking place after such an 'incubation' period, i.e.
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