Objective: The objective of this study was to present the clinical, histopathologic, and radiographic findings of a unique case of intimal sarcoma (IS) embolus presenting as a large vessel occlusion causing an ischemic stroke without a detectable primary tumor site.
Methods: Extensive examinations, multimodal imaging, laboratory testing, and histopathologic analysis were used in evaluation.
Results: We report the case of a patient who presented with acute embolic ischemic stroke and was found to have IS based on a histopathologic evaluation of his embolectomy specimen. Subsequent comprehensive imaging studies failed to detect a primary tumor site. Multidisciplinary interventions including a course of radiotherapy were performed. The patient died of recurrent multifocal strokes 92 days after diagnosis.
Discussion: Meticulous histopathologic analysis should be conducted on cerebral embolectomy specimens. Histopathology may be useful in diagnosing IS.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9973323 | PMC |
| http://dx.doi.org/10.1212/CPJ.0000000000200129 | DOI Listing |
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