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| http://dx.doi.org/10.18295/squmj.5.2022.037 | DOI Listing |
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Bullous Symmetric Drug-Related Intertriginous and Flexural Exanthem Secondary to Trimethoprim/Sulfamethoxazole.
Cureus
November 2024
Department of Dermatology, University of Florida College of Medicine, Gainesville, USA.
Symmetric drug-related intertriginous and flexural exanthem (SDRIFE) is a rare delayed-type hypersensitivity reaction that is considered a variant of systemic allergic contact dermatitis. It is typically triggered by drugs such as beta-lactam antibiotics or antihypertensives. The reaction presents as erythema with flexural prominence.
View Article and Find Full Text PDFAGA Clinical Practice Update on Esophageal Dysfunction Due to Disordered Immunity and Infection: Expert Review.
Clin Gastroenterol Hepatol
December 2024
Division of Gastroenterology, University of Utah, Salt Lake City, Utah. Electronic address:
Article Synopsis
- The American Gastroenterological Association (AGA) commissioned this expert review to provide guidance on diagnosing infectious and immune-mediated esophageal disorders, which are often under-recognized and lead to dysfunction and health costs.
- The review offers Best Practice Advice (BPA) statements based on published literature and expert opinions, but lacks formal evidence ratings due to the absence of systematic reviews.
- Increased awareness among gastroenterologists regarding these disorders can enhance patient care by improving diagnosis and limiting unnecessary medical procedures, particularly in patients presenting with dysphagia, heartburn, and odynophagia.
A case of eosinophilic granulomatosis with polyangiitis preceded by allergic bullous lesions.
Mod Rheumatol Case Rep
January 2025
Nephrology and Rheumatology center, and Okinaka Memorial Institute for Medical Research, Toranomon Hospital, Tokyo, 105-8470, Japan.
Article Synopsis
- A 62-year-old man with diabetes was hospitalized due to symptoms like numbness in his legs and widespread blistering on his skin.
- Diagnostic tests revealed a condition called mononeuritis multiplex and significant eosinophil presence, leading to the diagnosis of eosinophilic granulomatosis with polyangiitis alongside allergic bullous lesions.
- Biopsies from his kidneys, muscles, and skin showed evidence of vasculitis and high eosinophilic infiltration, while immunohistological studies indicated cell death involving eosinophils, referred to as eosinophil ETosis.
Pseudoephedrine-induced Fixed Drug Eruption in a Scuba Diver With Recurrent Palmoplantar Exfoliation.
J Prev Med Public Health
November 2024
King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Bangkok, Thailand.
This report presents a case of pseudoephedrine-induced non-pigmented bullous fixed drug eruption (NBFDE) manifesting as recurrent palmoplantar exfoliation in a scuba diver. It emphasizes the importance of considering drug allergies in the differential diagnosis when divers present with peeling hands and soles. A 38-year-old female scuba diver experiencing recurrent palmoplantar exfoliation underwent a clinical evaluation, patch testing, an interferon-gamma enzyme-linked immunospot (ELISpot) assay, and graded drug challenges with pseudoephedrine and phenylephrine.
View Article and Find Full Text PDFCase of Bullous Pemphigoid Masquerading as Adult-Onset Atopic Dermatitis.
Perm J
September 2024
Kaiser Permanente Bernard J Tyson School of Medicine, Pasadena, CA, USA.
The majority of dermatitis cases in adults result from chronic or relapsing atopic dermatitis in childhood. Adult-onset atopic dermatitis, also known as idiopathic chronic eczematous eruption of aging (CEEA), is a phenomenon seen in adults 50 years and older with no prior history of atopic dermatitis. CEEA is often a diagnosis of exclusion after ruling out more serious causes of dermatitis including bullous pemphigoid (BP), allergic conditions, and hematologic malignancies.
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