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Chemical recycling of polymer contaminated poly(ethylene terephthalate) by neutral hydrolysis.
Waste Manag
January 2025
Plastic and Polymer Engineering, Department of Biological and Chemical Engineering, Aarhus University, Aabogade 40, DK-8200 Aarhus N., Denmark. Electronic address:
Plastic recycling is gaining traction to reduce the demand for fossil resources for plastic production. Poly(ethylene terephthalate) (PET), mainly used in the packaging and textile sectors, is often isolated in the sinking fraction during the density-based separation of mixed plastic waste streams. The heterogeneity of the sinking fraction makes direct mechanical recycling of PET impossible.
View Article and Find Full Text PDFPharmacological management of Idiopathic Pulmonary Fibrosis: current and emerging options.
Expert Opin Pharmacother
February 2021
Interstitial Lung Disease Unit, Respiratory Department, Royal Brompton Hospital, London, UK.
Introduction: Idiopathic Pulmonary Fibrosis is a chronic, progressive lung disease characterized by worsening lung scarring and the radiological/histological pattern of usual interstitial pneumonia. Substantial progress has been made in the clinical management of IPF in the last decade. The two novel antifibrotics, Nintedanib and Pirfenidone have changed the landscape of IPF, by hindering disease progression; however, the drugs have significant discontinuation rates, due to adverse events and do not offer a definitive cure, as such IPF remains a deleterious disease with poor survival.
View Article and Find Full Text PDFAdvancing Pan-cancer Gene Expression Survial Analysis by Inclusion of Non-coding RNA.
RNA Biol
November 2020
Comprehensive Cancer Center, University of New Mexico, Albuquerque, NM, USA.
Non-coding RNAs occupy a significant fraction of the human genome. Their biological significance is backed up by a plethora of emerging evidence. One of the most robust approaches to demonstrate non-coding RNA's biological relevance is through their prognostic value.
View Article and Find Full Text PDFLoss of MIEF1/MiD51 confers susceptibility to BAX-mediated cell death and PINK1-PRKN-dependent mitophagy.
Autophagy
December 2019
Department of Biological Sciences, Faculty of Science, National University of Singapore, Singapore, Singapore.
Mitochondrial dynamics is highly implicated in a plethora of cellular processes including apoptosis and mitophagy. However, little is known about the scope and precise functions of mitochondrial dynamics proteins for mitochondrial quality control and cellular homeostasis. Whether mitochondrial dynamics proteins serve in cellular processes reliant on mitochondrial fission-fusion is still not fully explored.
View Article and Find Full Text PDFAutophagy-dependent secretion: mechanism, factors secreted, and disease implications.
Autophagy
October 2019
Departments of Otolaryngology, University of Kansas Medical Center, Kansas City , KS , USA.
Although best understood as a degradative pathway, recent evidence demonstrates pronounced involvement of the macroautophagic/autophagic molecular machinery in cellular secretion. With either overexpression or inhibition of autophagy mediators, dramatic alterations in the cellular secretory profile occur. This affects secretion of a plethora of factors ranging from cytokines, to granule contents, and even viral particles.
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