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Osteoarthritis of the knee is a common cause of pain, functional disability, and reduced quality of life in the elderly. Despite its prevalence, there are limited currently available noninvasive treatment options. MRI-guided focused ultrasound (MRgFUS) is a noninvasive thermal ablation method which is used in a spectrum of musculoskeletal conditions.

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  • Metabolic syndrome is a growing public health issue globally, particularly linked to diseases like type 2 diabetes, and this study focuses on its prevalence among type 2 diabetic patients in Ethiopia.
  • Researchers analyzed various studies to determine the pooled prevalence and factors contributing to metabolic syndrome, employing robust statistical methods to ensure accuracy and reliability of findings.
  • The study found a significant prevalence of metabolic syndrome among type 2 diabetes patients in Ethiopia, with rates ranging from about 47% to over 59% depending on different diagnostic criteria, and it identified several risk factors associated with the condition.
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  • Patients with rare cancers experience longer diagnostic delays and fewer treatment options, which can negatively affect their employment status both before and after diagnosis.
  • A study comparing 16,203 rare cancer patients to 23,295 common cancer patients found that those with rare cancers were more likely to become work-disabled before diagnosis and more likely to pursue self-employment after diagnosis.
  • Younger patients and those on temporary contracts were more likely to transition to self-employment, highlighting the need for improved awareness and care for rare cancer to minimize negative work outcomes.
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  • The study examines trends and epidemiology of pediatric burns in Dutch burn centers from 2009 to 2022, highlighting the need for effective prevention strategies and resource allocation.
  • The analysis revealed a gradual increase in pediatric burn admissions, with a temporary decrease during the COVID-19 pandemic; 77% of patients were overnight admissions.
  • Young children (ages 0-3) were the most affected group, and a shift toward shorter hospital stays and increased day admissions was noted, especially during the pandemic.
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Background: Juvenile systemic lupus erythematosus (SLE) is a severe, life-threatening disease. However, the role of rituximab in managing juvenile SLE remains undefined, although early biological intervention may improve disease outcomes.

Aim: To assess the differences in the outcomes of different types of rituximab administration (early and late).

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