[Research Progress on Epigenetics in Endometriosis].

Zhongguo Yi Xue Ke Xue Yuan Xue Bao

Department of Gynecology and Obstetrics, Peking University First Hospital,Beijing 100034,China.

Published: February 2023

Epigenetics refers to heritable changes in gene expression and function without alterations in gene sequences,including DNA methylation,histone modification,and non-coding RNAs.Endometriosis is a benign gynecological disease that affects the fertility and health of reproductive-age women,the etiology of which remains unclear.The recent studies have demonstrated that epigenetics plays a key role in the occurrence and development of endometriosis.This article reviews the research progress in the regulatory mechanism and application of epigenetics in endometriosis.

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http://dx.doi.org/10.3881/j.issn.1000-503X.14739DOI Listing

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