Regeneration, as a fascinating scientific field, refers to the ability of animals replacing lost tissue or body parts. Many metazoan organisms have been reported with the regeneration phenomena, but showing evolutionarily variable abilities. As the most diverse metazoan taxon, hundreds of insects show strong appendage regeneration ability. The regeneration process and ability are dependent on many factors, including macroscopic physiological conditions and microscopic molecular mechanisms. This article reviews research progress on the physiological conditions and internal underlying mechanisms controlling appendage regeneration in insects.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978051 | PMC |
| http://dx.doi.org/10.1186/s13619-022-00156-1 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
"Pattern Regulation in Epimorphic Fields", aka the Polar Coordinate Model.
Dev Biol
January 2025
Department of Life Sciences, University of Bath, Claverton Down, Bath BA2 7AY, UK.
The Polar Coordinate Model (PCM) was a model, published in 1976, to account for the properties of distal regeneration in the appendages of insects and vertebrates. It had considerable impact at the time and has continued to be cited ever since. This article describes the work that led up to the model, the genesis of the model itself, its strengths and weaknesses, and its long term impact.
View Article and Find Full Text PDFElectroactive Asymmetric Dressing for Spatiotemporal Deep Burn Scarless Healing and Management.
Adv Healthc Mater
January 2025
Department of Biomedical Engineering, City University of Hong Kong, Hong Kong, 999077, China.
Burn care and treatment differ markedly from other types of wounds, as they are significantly more prone to infections and struggle to maintain fluid balance post-burn. Moreover, the limited self-healing abilities exacerbate the likelihood of scar formation, further complicating the recovery process. To tackle these issues, an asymmetric wound dressing comprising a quercetin-loaded poly(3-hydroxybutyrate-co-4-hydroxybutyrate) (P34HB@Qu) hydrophilic layer and a zinc oxide nanoparticle-loaded, thermally treated polyvinylidene fluoride (HPVDF@ZnO) hydrophobic layer is designed.
View Article and Find Full Text PDFEnzyme-crosslinked hyaluronic acid hydrogel scaffolds for BMSCs microenvironment and wound healing.
Int J Biol Macromol
January 2025
Department of Dermatology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, PR China. Electronic address:
Tissue engineering utilizing hydrogel scaffolds in combination with exogenous stem cells holds significant potential for promoting wound regeneration. However, the microenvironment provided by existing skin tissue engineering scaffold materials is often inadequate. Herein, we demonstrate an enzyme-crosslinked hyaluronic acid hydrogel to provide a growth microenvironment for exogenous bone marrow mesenchymal stem cells and promote acute wound healing.
View Article and Find Full Text PDFOrganoids in skin wound healing.
Burns Trauma
January 2025
Department of Pathology, Shengjing Hospital of China Medical University, No. 36 Sanhao Street, Shenyang, Liaoning 110004, China.
Stem cells (SCs) can self-replicate and differentiate into multiple lineages. Organoids, 3D cultures derived from SCs, can replicate the spatial structure and physiological characteristics of organs . Skin organoids can effectively simulate the physiological structure and function of skin tissue, reliably restoring the natural skin ecology in various environments.
View Article and Find Full Text PDFTargeting mA demethylase FTO to heal diabetic wounds with ROS-scavenging nanocolloidal hydrogels.
Biomaterials
December 2024
Department of Developmental Biology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, 510515, PR China; State Key Laboratory of Organ Failure Research, Southern Medical University, Guangzhou, 510515, PR China. Electronic address:
Chronic diabetic wounds are a prevalent and severe complication of diabetes, contributing to higher rates of limb amputations and mortality. N6-methyladenosine (mA) is a common RNA modification that has been shown to regulate tissue repair and regeneration. However, whether targeting mA could effectively improve chronic diabetic wound healing remains largely unknown.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!