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Dementia Care Practice.
Alzheimers Dement
December 2024
University of Connecticut School of Medicine, Farmington, CT, USA.
Background: This presentation maps the journey of an evidence-based dementia care program from effectiveness trial design to adoption by policymakers as an ongoing program available to eligible older adults living at home with dementia and their care partners. Care of People with Dementia in their Environments (COPE) is a non-pharmacologic program that seeks to maximize physical function and quality of life in people with dementia and build dementia management skills in care partners. Efficacy trial results showed that, compared to controls, people with dementia receiving COPE had greater functional independence in activities of daily living and care partners receiving COPE reported improved well-being and increased confidence using dementia management skills.
View Article and Find Full Text PDFLegal Recreational Cannabis Sales and Opioid-Related Mortality in the 5 Years Following Cannabis Legalization in Canada: A Granger Causality Analysis.
Cannabis
December 2024
Peter Boris Centre for Addictions Research, St. Joseph's Healthcare Hamilton.
Objective: Little is known about the population-level impact of recreational cannabis legalization on trends in opioid-related mortality. Increased access to cannabis due to legalization has been hypothesized to reduce opioid-related deaths because of the potential opioid-sparing effects of cannabis. The objective of this study was to examine the relations between national retail sales of recreational (non-medical) cannabis and opioid overdose deaths in the 5 years following legalization in Canada.
View Article and Find Full Text PDFRemotely delivered weight management for people with long COVID and overweight: the randomized wait-list-controlled ReDIRECT trial.
Nat Med
January 2025
General Practice and Primary Care, School of Health and Wellbeing, University of Glasgow, Glasgow, UK.
Long COVID (LC) is a complex multisymptom condition with no known disease-modifying treatments. This wait-list-controlled open-label trial tested whether a remotely delivered structured weight management program could improve respective LC symptoms in people living with overweight. Adults with LC (symptoms >12 weeks) and body mass index >27 kg m (>25 kg m for South Asians) were randomized (n = 234, 1:1) to control (n = 116, usual care) or the remotely delivered structured weight management (n = 118, total diet replacement (850 kcal per day) for 12 weeks, followed by food reintroduction and weight loss maintenance support) via minimization and randomization (80:20) to balance dominant LC symptom, sex, age, ethnicity and postcode-based index of multiple deprivation between groups.
View Article and Find Full Text PDFBalancing fairness and efficiency in dynamic vaccine allocation during major infectious disease outbreaks.
Sci Rep
January 2025
School of Economics and Management, Beijing Jiaotong University, No.3 Shangyuan Cun, Haidian District, Beijing, 100044, People's Republic of China.
The outbreak of novel infectious diseases presents major public health challenges, highlighting the urgency of accelerating vaccination efforts to reduce morbidity and mortality. Vaccine allocation has become a crucial societal concern. This paper introduces a dynamic vaccine allocation model that considers demand uncertainty and vaccination willingness, focusing on the trade-off between fairness and efficiency.
View Article and Find Full Text PDFRegional green economies and Bitcoin's electricity consumption: Paving the way for global sustainability.
J Environ Manage
January 2025
Department of Accounting and Finance, Nottingham Trent University, Nottingham, UK. Electronic address:
In the context of global sustainability goals, it is imperative to examine the interplay between emerging financial technologies and environmental objectives, which in turn offers insights into the implications of such technologies on sustainable investments and environmental policy decisions. Accordingly, this study investigates the influence of Bitcoin's energy consumption (BEC), as a representative of the cryptocurrency market, on the regional green economy indices of the United States, Europe, and Asia. Utilizing both unfiltered and filtered data, we conduct empirical analyses from both static and dynamic perspectives to account for the causal relationships that emerged during critical market developments, employing novel algorithms including forward recursive, rolling windows, and recursive rolling.
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