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http://dx.doi.org/10.1136/bcr-2022-252500 | DOI Listing |
Oxf Med Case Reports
November 2024
Department of Dermatology, Tishreen University Hospital, Lattakia, Syria.
Rupioid psoriasis is a rare subtype of psoriasis characterized by distinctive lesions resembling oyster shells, known as rupioid lesions. This subtype is particularly uncommon in the pediatric population and is often associated with poor treatment compliance. Ustekinumab, an IgG monoclonal antibody, targets IL-12 and IL-23, reducing the release of proinflammatory cytokines TNFα, IL-2, and IL-17α, which play vital roles in psoriasis pathophysiology.
View Article and Find Full Text PDFJ Am Acad Dermatol
November 2024
HCA Healthcare/USF Morsani College of Medicine GME, HCA Florida Largo Hospital, Largo, Florida.
Cureus
February 2024
Department of Precision and Regenerative Medicine and Ionian Area, University of Bari Aldo Moro, Bari, ITA.
We report the case of a 77-year-old man affected by a poorly differentiated metastatic pulmonary adenocarcinoma who, after the first course of therapy with cisplatin-pemetrexed-pembrolizumab treatment, developed rupioid psoriasis. We decided to discontinue pembrolizumab for four weeks until lesions improved and to start therapy with apremilast (an oral small molecule phosphodiesterase (PDE)4 inhibitor) in combination with systemic methylprednisolone 16 mg/day with consequent tapering until discontinuation in a few weeks. After accomplishing three months of treatment with apremilast, the patient gained complete remission of the rupioid lesions.
View Article and Find Full Text PDFSemergen
October 2023
Department of Dermatology, Hospital Universitario San Cecilio, Granada, Spain.
Indian J Dermatol Venereol Leprol
April 2023
Department of Dermatology, Venereology & Leprosy, Era's Lucknow Medical College and Hospital, Lucknow, Uttar Pradesh, India.
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