The encapsulation of icosahedral -dicarbadodecaborane (-, -, and -carboranes, ) as guest molecules at the intrinsic cavities of the three isostructural tetrahedral cages [{Pd(NPr)PO}(Cl-AN)] (), [{Pd(NPr)PO}(Br-AN)] (), and [{Pd(NPr)PO}(H-AN)] () was studied. The formation of definite host-guest assemblies was probed with mass spectrometry, IR, and NMR spectral analysis. 2D DOSY H NMR of the ⊂Cage systems showed similar diffusion coefficient () values for the host and guest species, signifying the encapsulation of these guests inside the cage assemblies. The hydrodynamic radius () derived from the values of the host and guest species further confirmed the encapsulation of the isomers at the cage pockets. The single-molecule energy optimization of the host-guest assemblies indicated the preferential binding of - as a guest inside the cages (-). The stabilization of these guests inside these cages was further attributed to various possible nonclassical C-H···X-type interactions.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/acs.inorgchem.2c04207 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Self-cascade catalytic system constructed using carbon dots and Au nanoparticles co-assembled on MIL-53(Fe)-NH as a three-in-one fluorescent nanozyme for multimodal detection of glucose and maltose in food.
Food Chem
December 2024
State Key Laboratory of Inorganic Synthesis and Preparative Chemistry, College of Chemistry, Jilin University, 2699 Qianjin Street, Changchun 130012, China. Electronic address:
Determination of glucose and maltose is crucial for food production and human health. Herein, a novel Au/CD@MIL-53(Fe)-NH self-cascade nanozyme was constructed via host-guest assembly with "three-in-one" features, including blue fluorescence, HO production as an oxidase mimic, and •OH generation as a peroxidase mimic. Theoretical and experimental results proved that the incorporation of carbon dots renders the composite with high peroxidase-like activity and extremely high affinity for HO (K: 0.
View Article and Find Full Text PDFNanocarriers for intracellular delivery of molecular payloads triggered by visible light.
Soft Matter
December 2024
Organic Chemistry Institute, University of Münster, Münster, Germany.
Stimuli-responsive nanocontainers have emerged as promising vehicles to deliver molecular payloads into the cytosol of cells in a spatially, temporally and dosage-controlled manner. These nanocontainers respond to a specific type of stimulus such as a change in redox status, enzymatic activity, pH, heat, light, and others. In this work, we introduce photoresponsive nanocontainers based on the self-assembly of vesicles with surface-confined cyclodextrin-adamantane host-guest chemistry.
View Article and Find Full Text PDFA supramolecular assembly strategy for the treatment of rheumatoid arthritis with ultrasound-augmented inflammatory microenvironment reprograming.
Biomaterials
May 2025
Strait Institute of Flexible Electronics (SIFE, Future Technologies), College of Photonic and Electronic Engineering, Fujian Key Laboratory of Flexible Electronics and Strait Laboratory of Flexible Electronics (SLoFE), Fujian Normal University, Fuzhou, 350117, China. Electronic address:
As regulators and promotors of joint erosion, pro-inflammatory M1-like macrophages play pivotal roles in the pathogenesis of rheumatoid arthritis (RA). Here, we develop a supramolecular self-assembly (PCSN@MTX) of molybdenum (Mo) based polyoxometalate (POM), β-cyclodextrin (β-CD), and methotrexate (MTX), in which the MTX is loaded by host-guest interaction. PCSN@MTX shows inhibition of synovial M1-like macrophages polarization to alleviate RA.
View Article and Find Full Text PDFAdvances in Chiral Macrocycles: Molecular Design and Applications.
Chemistry
December 2024
South China University of Technology, School of Chemistry and Chemical Engineering, 381 Wushan Road, 510641, Guangzhou, CHINA.
Chiral macrocycles have recently emerged as promising materials for enantioselective recognition, asymmetric catalysis, and circularly polarized luminescence (CPL) due to their terminal-free structure, preorganized chiral cavities, and unique host-guest and self-assembly properties. This review summarizes recent advances in the design and synthesis of chiral macrocycles with central, axial, helical, and planar chirality, each imparting distinct structural and chiroptical characteristics. We highlight key strategies for constructing these macrocycles and their applications in optoelectronic and catalytic systems.
View Article and Find Full Text PDFA FRET Autophagy Imaging Platform by Macrocyclic Amphiphile.
Angew Chem Int Ed Engl
December 2024
College of Chemistry, State Key Laboratory of Elemento-Organic Chemistry, Key Laboratory of Functional Polymer Materials (Ministry of Education), Frontiers Science Center for New Organic Matter, Collaborative Innovation Center of Chemical Science and Engineering, Nankai University, 300071, Tianjin, China.
Autophagy is a ubiquitous process of organelle interaction in eukaryotic cells, in which various organelles or proteins are recycled and operated through the autophagy pathway to ensure nutrient and energy homeostasis. Although numerous fluorescent probes have been developed to image autophagy, these environment-responsive probes suffer from inherent deficiencies such as inaccuracy and limited versatility. Here, we present a modular macrocyclic amphiphile Förster Resonance Energy Transfer (FRET) platform (SC6A12C/NCM, SN), constructed through the amphiphilic assembly of sulfonatocalix[6]arene (SC6A12C) with N-cetylmorpholine (NCM) for lysosome targeting.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!