Low-light imaging is challenging in regimes where low-noise detectors are not yet available. One such regime is the shortwave infrared where even the best multipixel detector arrays typically have a noise floor in excess of photons per pixel per frame. We present a homodyne imaging system capable of recovering both intensity and phase images of an object from a single frame despite an illumination intensity of photon per pixel. We interfere this weak signal which is below the noise floor of the detector with a reference beam that is times brighter, record the resulting interference pattern in the spatial domain on a detector array, and use Fourier techniques to extract the intensity and phase images. We believe our approach could vastly extend the range of applications for low-light imaging by accessing domains where low-noise cameras are not currently available and for which low-intensity illumination is required.
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http://dx.doi.org/10.1073/pnas.2216678120 | DOI Listing |
Carbohydr Polym
March 2025
Plant Fiber Material Science Research Center, State Key Laboratory of Pulp and Paper Engineering, School of Light Industry and Engineering, South China University of Technology, Guangzhou 510640, China; Guangdong Provincial Key Laboratory of Plant Resources Biorefinery, No. 100, West Outer Ring Road, Guangzhou University Town, Panyu District, Guangzhou 510006, China.
Ancient documents and artworks are invaluable cultural heritage artworks that require careful preservation. Traditional methods for assessing their physical and chemical properties-such as tearing index, tensile index, water absorption, and pH-are often destructive, risking irreversible damage. This study introduces a novel, non-destructive approach using Short-Wave Near-Infrared (SWNIR) hyperspectral imaging (HSI) combined with advanced machine learning models.
View Article and Find Full Text PDFACS Photonics
January 2025
Photonic Nanomaterials, Istituto Italiano di Tecnologia, 16163 Genova, Italy.
Colloidal semiconductor nanocrystals (NCs) are an efficient and cost-effective class of nanomaterials for optoelectronic applications. Advancements in NC-based optoelectronic devices have resulted from progress in synthetic chemistry, adjustable surface properties, and optimized device architectures. Semiconductor nanoplatelets (NPLs) stand out among other NCs due to their precise growth control, yielding uniform thickness with submonolayer roughness.
View Article and Find Full Text PDFResearch (Wash D C)
January 2025
Research Center for Advanced Detection Materials and Medical Imaging Devices, Institute of Biomedical and Health Engineering, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, P. R. China.
Fluorescence imaging, a highly sensitive molecular imaging modality, is being increasingly integrated into clinical practice. Imaging within the second near-infrared biological window (NIR-II; 1,000 to 1,700 nm), also referred to as shortwave infrared, has received substantial attention because of its markedly reduced autofluorescence, deeper tissue penetration, and enhanced spatiotemporal resolution as compared to traditional near-infrared (NIR) imaging. Indocyanine green (ICG), a US Food and Drug Administration-approved NIR fluorophore, has long been used in clinical applications, including blood vessel angiography, vascular perfusion monitoring, and tumor detection.
View Article and Find Full Text PDFSci Rep
January 2025
Fischell Department of Bioengineering, University of Maryland, College Park, USA.
The development of optical sensors for label-free quantification of cell parameters has numerous uses in the biomedical arena. However, using current optical probes requires the laborious collection of sufficiently large datasets that can be used to calibrate optical probe signals to true metabolite concentrations. Further, most practitioners find it difficult to confidently adapt black box chemometric models that are difficult to troubleshoot in high-stakes applications such as biopharmaceutical manufacturing.
View Article and Find Full Text PDFSensors (Basel)
January 2025
Research and Development Center of Optoelectronic Hybrid IC, Guangdong Greater Bay Area Institute of Integrated Circuit and System, Guangzhou 510535, China.
Short-wave infrared (SWIR) imaging has a wide range of applications in civil and military fields. Over the past two decades, significant efforts have been devoted to developing high-resolution, high-sensitivity, and cost-effective SWIR sensors covering the spectral range from 0.9 μm to 3 μm.
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