AI Article Synopsis
- The study examines the differences between solar melanomas (like LMM) and non-solar melanomas (like ALM), highlighting that ALM is not influenced by chronic sun exposure.
- Researchers analyzed data from 1,056 Caucasian patients diagnosed with ALM and LMM between 2012 and 2020.
- Findings suggest that ALM has a less favorable prognosis than LMM, indicating that non-solar melanomas may be more aggressive, stressing the need for sentinel lymph node biopsies in ALM cases.
Article Abstract
Background: Skin phototype, latitude and sun exposure are classic risk factors for melanomas but are not relevant to acrolentiginous melanomas (ALM). ALM is not related to chronic sun exposure because the thick stratum corneum acts as a barrier to penetration of UV rays, whereas LMM occurs in skin with high photoaging due to chronic sun exposure.
Objectives: This study aimed to determine if any difference exists between "solar" melanomas and "non-solar" melanomas based on a comparison between LMM and ALM.
Materials & Methods: We extracted all data for ALM and LMM patients, from March 2012 to September 2020, from the RIC-Mel national database to perform a descriptive cohort analysis of 1,056 Caucasian cases.
Conclusion: The profiles of solar-related and non-solar melanoma seem to be different, and prognostic factors of ALM at diagnosis are less favourable compared to LMM, suggesting that non-solar melanoma is more aggressive than solar-related melanoma and that sentinel lymph node biopsy should be performed.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1684/ejd.2022.4357 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!