Galenic formulations of : comparison of the chemical properties of extracts obtained by simple protocols using lipidic vehicles.

Nat Prod Res

Departamento de Química y Bioquímica, Facultad de Ciencias Exactas y Naturales, Universidad Nacional de Mar del Plata-CONICET, Funes 3350, 7600, Mar del Plata, Buenos Aires, Argentina.

Published: January 2024

AI Article Synopsis

  • The increasing acceptance of medicinal cannabis as a complementary therapy alongside traditional medicine has led to global changes in regulations regarding its use.
  • The study focused on developing low-cost and efficient methods for producing medicinal cannabis oils that are easy to prepare and use.
  • The resulting formulations exhibit known concentrations of key compounds and demonstrate enhanced antioxidant properties, suggesting a safe approach to creating standardized cannabis products.

Article Abstract

The growing use of as a complementary therapy to allopathic medicine has brought about the modification of laws for its use worldwide. This entails the need to harmonize the methods of galenic preparations in pharmacies and cannabis-specialized non-governmental organizations as well as for self-provision as contemplated in some current legislation, such as that of Argentina. Thus, this work aimed to study simple and efficient methods to produce medicinal cannabis oils that require low-cost equipment and few handling steps. The final formulas allowed the obtaining of preparations of known concentrations of neutral cannabinoids, total polyphenol content, total flavonoid content, and antioxidant capacity. These methods allow for the selection of convenient vehicles and access to safe medicinal products of standardized quality. Our results show that cannabis extraction can be efficiently performed by directly using long-chain lipidic vehicles as extractants, resulting in a formulation with maximized oxidizing capacity and potentially extending its durability.

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Source
http://dx.doi.org/10.1080/14786419.2023.2184357DOI Listing

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