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Squamomelanocytic Tumor, An Entity Still Shrouded in Mystery: Case Report and Literature Review.
Dermatopathology (Basel)
January 2025
Section of Molecular Pathology, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari "Aldo Moro", 70124 Bari, Italy.
Cutaneous squamomelanocytic tumor (SMT) is a very rare cutaneous malignancy, composed of a dual phenotypic population of both malignant melanocytes and keratinocytes, intimately intermingled together. Herein, we report a new case of a SMT occurring in an 82-year-old man, located on the scalp. Histopathology revealed a mixed population consisting of squamous cell carcinoma and melanoma within the same lesion, also confirmed using immunohistochemical staining for high molecular-weight cytokeratins (HMWCKs) and Melan-A.
View Article and Find Full Text PDFLong noncoding RNA, is associated with aneuploidy and its magnitude of expression level is dependent on P53 status.
Front Cell Dev Biol
December 2024
Department of Medical Biotechnology, School of Biological Sciences, Ramakrishna Mission Vivekananda Educational and Research Institute (RKMVERI), Kolkata, India.
Introduction: Long non-coding RNAs (lncRNAs) are a fascinating, but still largely uncharacterized, class of genes. Recently, lncRNAs have attracted significant attention due to their emerging functions in development and disease. The role of lncRNAs in chromosome instability or aneuploidy is not extensively studied.
View Article and Find Full Text PDFThe modeling of human implantation and early placentation: achievements and perspectives.
Hum Reprod Update
December 2024
C.S. Mott Center for Human Growth and Development, Wayne State University, Detroit, MI, USA.
Background: Successful implantation is a critical step for embryo survival. The major losses in natural and assisted human reproduction appeared to occur during the peri-implantation period. Because of ethical constraints, the fascinating maternal-fetal crosstalk during human implantation is difficult to study and thus, the possibility for clinical intervention is still limited.
View Article and Find Full Text PDFVideo evidence of mountings by female-plumaged birds of paradise (Aves: Paradisaeidae) in the wild: Is there evidence of alternative mating tactics?
Ethology
May 2024
Konrad Lorenz Institute of Ethology, University of Veterinary Medicine, Vienna, Austria.
The bewildering courtship phenotypes of male birds of paradise () represent a classic example of sexual selection through mate choice. While the majority of sexual selection studies have focused on either mate choice or intrasexual competition, males across a variety of taxa adopt alternative mating tactics as additional means of obtaining fertilization when they are otherwise unable to. For example, across various polygynous birds, subordinate males engage in sneak copulations, which may offset the fitness costs of prolonged subordinate periods.
View Article and Find Full Text PDFHydin as the Candidate Master Sex Determination Gene in Channel Catfish (Ictalurus punctatus) and Its Epigenetic Regulation.
Mar Biotechnol (NY)
November 2024
Department of Biology, College of Arts and Sciences, Tennessee Technological University, Cookeville, TN, 38505, USA.
Sex determination is a fascinating area of research. To date, more than 20 master sex determination (SD) genes have been reported from vertebrate animals. With channel catfish (Ictalurus punctatus), much work has been conducted to determine its master SD gene, ranging from genetic linkage mapping, genome-wide association (GWA) analysis, genome sequencing, comparative genome analysis, epigenomic analysis, transcriptome analysis, and functional studies.
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