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| http://dx.doi.org/10.5588/ijtld.22.0372 | DOI Listing |
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Urinary lipoarabinomannan for diagnosis of Tuberculosis in an HIV-negative population: A scoping review.
Afr J Prim Health Care Fam Med
December 2024
Department of Internal Medicine, Prince Mshiyeni Memorial Hospital, Durban.
Background: Tuberculosis (TB) remains a leading cause of mortality in low-resource settings and poses a diagnostic challenge in human immunodeficiency virus (HIV)-negative populations because of limitations in traditional diagnostic methods such as sputum smear microscopy (SSM) and sputum Xpert Ultra. There is a lack of effective, non-invasive diagnostic options for TB diagnosis in HIV-negative populations. This scoping review explores the potential of urinary lipoarabinomannan (ULAM) as a point-of-care diagnostic tool for Mycobacterium tuberculosis (MTB) in HIV-negative individuals.
View Article and Find Full Text PDFThe Disturbed Microbial Niches of Itchy Scalp.
J Cosmet Dermatol
January 2025
State Key Laboratory of Microbial Metabolism, Joint International Research Laboratory of Metabolic and Developmental Sciences, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China.
Background: Scalp itch without evident cause is an uncomfortable symptom that annoys many people in life but lacks adequate attention in academic.
Aims: To investigate the relationship between scalp itching and microorganisms, and identify the key microbes and predicted functions associated with scalp itching, furtherly to provide useful targets for scalp itch solution.
Methods: We performed microbial comparison between 44 normal subjects and 89 subjects having scalp itching problem with un-identified origin based on 16S rRNA gene sequencing and ddPCR (digital droplet PCR), and identified itch relevant microbes and predicted functions.
Bacteriological quality and predictors of raw meat collected from municipal slaughterhouse and butcher shops in northeast, Ethiopia.
Front Public Health
January 2025
Department of Environmental Health, College of Medicine and Health Sciences, Debre Markos University, Debre Markos, Ethiopia.
Background: Meat is a good source of protein in the human diet, and more than three-quarters of the world's population consumes it. It is the most perishable food item since it has enough nutrients to enable microbial growth. In underdeveloped nations, animals are routinely slaughtered and sold in unsanitary conditions, compromising the bacteriological quality and safety of the meat received from the animals.
View Article and Find Full Text PDFMetagenomic next-generation sequencing for the clinical identification of spinal infection-associated pathogens.
Front Cell Infect Microbiol
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Department of Spine Surgery, Fuzhou Second General Hospital, Fuzhou, Fujian, China.
Background: This study aimed to evaluate the efficacy of metagenomic next-generation sequencing (mNGS) technology for identifying pathogens associated with spinal infection (SI).
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Application of metagenomic next-generation sequencing in the diagnosis of post-stroke infections: a case series study using multiple sample types.
Front Cell Infect Microbiol
January 2025
Department of Neurology, The First Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong, China.
Background: Metagenomic high-throughput sequencing (mNGS) represents a powerful tool for detecting nucleic acids from various pathogens, such as bacteria, fungi, viruses and parasites, in clinical samples. Despite its extensively employed in the pathogen diagnosis for various infectious diseases, its application in diagnosing stroke-related infection, and its potential impact on clinical decision-making, anti-infection treatment, clinical intervention, and patient prognosis remain insufficiently explored. Additionally, while mNGS offers promising potential, it facts limitations related to sensitivity, specificity, cost, and standardization, which could influence its integration into routine clinical practice.
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