AI Article Synopsis
- Transmissible gastroenteritis virus (TGEV) poses significant risks to pig farming, causing high mortality rates among piglets.
- The virus is evolving rapidly, with some strains able to infect different species, complicating detection and prevention efforts.
- The paper reviews TGEV's biological properties, factors influencing its virulence, advancements in understanding its effects on cell processes, and raises concerns about its potential zoonotic risks.
Article Abstract
Transmissible gastroenteritis virus (TGEV) is a member of the alphacoronavirus genus, which has caused huge threats and losses to pig husbandry with a 100% mortality in infected piglets. TGEV is observed to be recombining and evolving unstoppably in recent years, with some of these recombinant strains spreading across species, which makes the detection and prevention of TGEV more complex. This paper reviews and discusses the basic biological properties of TGEV, factors affecting virulence, viral receptors, and the latest research advances in TGEV infection-induced apoptosis and autophagy to improve understanding of the current status of TGEV and related research processes. We also highlight a possible risk of TGEV being zoonotic, which could be evidenced by the detection of CCoV-HuPn-2018 in humans.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9958687 | PMC |
| http://dx.doi.org/10.3390/v15020359 | DOI Listing |
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