AI Article Synopsis
- The study analyzed RSV infections in children under 3 years old in 15 Pediatric Emergency Departments across different years (2019, 2020, 2021) to understand the impact of COVID-19 restrictions.
- There was a significant increase in RSV cases in 2021 compared to 2019 and 2020, particularly among 2-3 year-olds, with the peak occurrence happening a month earlier in 2021.
- Despite the increase in RSV admissions in 2021, the severity of the infections remained consistent across all years studied, indicating a shift in the age demographic affected by RSV post-COVID-19.
Article Abstract
The restrictive measures adopted worldwide against SARS-CoV-2 produced a drastic reduction in respiratory pathogens, including RSV, but a dramatic rebound was thereafter reported. In this multicenter retrospective observational study in 15 Pediatric Emergency Departments, all children <3 years old with RSV infection admitted between 1 September and 31 December 2021 were included and compared to those admitted in the same period of 2020 and 2019. The primary aim was to evaluate RSV epidemiology during and after the COVID-19 pandemic peak. The secondary aims were to evaluate the clinical features of children with RSV infection. Overall, 1015 children were enrolled: 100 in 2019, 3 in 2020 and 912 in 2021. In 2019, the peak was recorded in December, and in 2021, it was recorded in November. Comparing 2019 to 2021, in 2021 the median age was significantly higher and the age group 2-3 years was more affected. Admissions were significantly higher in 2021 than in 2020 and 2019, and the per-year hospitalization rate was lower in 2021 (84% vs. 93% in 2019), while the duration of admissions was similar. No difference was found in severity between 2019-2020-2021. In conclusion, after the COVID-19 pandemic, an increase in RSV cases in 2021 exceeding the median seasonal peak was detected, with the involvement of older children, while no difference was found in severity.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963567 | PMC |
| http://dx.doi.org/10.3390/v15020280 | DOI Listing |
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