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Cumulative Social Disadvantage and Medicinal Cannabis Use Among Younger Adults in Rural Communities: A Mixed Methods Approach.
J Psychoactive Drugs
January 2025
Center for Critical Public Health, The Institute for Scientific Analysis, Alameda, CA, USA.
This mixed-methods study investigated the role of medicinal cannabis use among younger adults who live in rural communities and experience high levels of cumulative social disadvantage (CSD). Results are based on cross-sectional surveys and online interviews with 153 younger adults (18-35-years old) in rural California. We assessed participants' levels of CSD (high, medium, and low) and examined associations with perceived general physical and mental health and with medicinal use of cannabis (MUC).
View Article and Find Full Text PDFImpact analysis of infant antibiotic exposure on the burden of asthma: a simulation modeling study.
Front Allergy
December 2024
Respiratory Evaluation Sciences Program, Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada.
Background: Infant antibiotic use is associated with increased risk of asthma. We examined the population impact of antibiotic exposure in the first year of life on the burden of pediatric asthma in British Columbia, Canada, using simulation modeling.
Methods: We performed a Bayesian meta-analysis of empirical studies to construct dose-response equations between antibiotic exposure in the first year of life and pediatric (<19 years of age) asthma.
Coral histology reveals consistent declines in tissue integrity during a marine heatwave despite differences in bleaching severity.
PeerJ
January 2025
Department of Biology, University of Pennsylvania, Philadelphia, PA, United States of America.
Marine heatwaves are starting to occur several times a decade, yet we do not understand the effect this has on corals across biological scales. This study combines tissue-, organism-, and community-level analyses to investigate the effects of a marine heatwave on reef-building corals. Adjacent conspecific pairs of coral colonies of and that showed contrasting phenotypic responses (, bleached .
View Article and Find Full Text PDFPrognostic significance of systemic immune inflammation index in patients with urothelial carcinoma: a systematic review and meta-analysis.
Front Oncol
December 2024
Department of Urology, Nanchong Central Hospital, The Second Clinical College, North Sichuan Medical College (University), Nanchong, Sichuan, China.
Objective: This review assessed the prognostic significance of the systemic immune inflammation index (SII) in patients with urothelial carcinoma.
Methods: We performed a systematic review and cumulative meta-analysis of the primary outcomes according to the PRISMA criteria, and assessed study quality. Seven databases were searched: Embase, PubMed, Cochrane Library, Web of Science, China National Knowledge Infrastructure, Wanfang, and SinoMed, from the creation of each database until October 2024.
Non-pharmacological Interventions for Preoperative Anxiety in Children: A Systematic Review and Network Meta-Analysis.
J Clin Nurs
January 2025
Department of Anesthesiology, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Aims: This study aimed to compare the efficacy of non-pharmacological interventions in children with preoperative anxiety.
Background: It is estimated that preoperative anxiety affects up to 60% of children which is associated with both immediate and long-term adverse outcomes. Several non-pharmacological interventions have been demonstrated to be effective, but further research is necessary to determine which is the most effective.
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