The purpose of the study was to produce an algorithm and surgical procedure for optimum treatment of pedal macrodactyly. Surgery was performed on 27 feet of 26 patients with a mean age of 33 months at the time of surgery (range: 7-108 months). A multi-technique procedure based on the involved elements of the foot (soft tissue, phalanx, or metatarsal, or a combination of these) was adopted. The intermetatarsal width ratio, phalanx spread angle, and metatarsal spread angle was used to evaluate the severity of the macrodactyly and the effect of treatment. The Oxford Ankle Foot Questionnaire for Children and the Questionnaire for Foot Macrodactyly were employed to evaluate the clinical results. Under the guidelines of the treatment algorithm, all patients were successfully operated on using the multi-technique procedure; the sizes of the affected feet decreased significantly. After a mean of 33 months (range: 18-42 months) follow-up, the intermetatarsal width ratio decreased from 1.13 to 0.93 ( < 0.05), the phalanx spread angle decreased from 31.3° to 17.9° ( < 0.05), the metatarsal spread angle decreased from 33.2° to 15.8° ( < 0.05), and the mean score for the Oxford Ankle Foot Questionnaire for Children improved from 42 to 47 ( < 0.05) after surgery. The mean score for the Questionnaire for Foot Macrodactyly was 9.35 at the time of follow-up. The goal of the treatment of pedal macrodactyly is to obtain a functional and cosmetically acceptable foot. This treatment algorithm and multi-technique procedure could fully satisfy this goal.
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http://dx.doi.org/10.1080/2000656X.2021.2017293 | DOI Listing |
J Chromatogr B Analyt Technol Biomed Life Sci
January 2025
Universite Claude-Bernard Lyon 1, CNRS, CPE-Lyon, CP2M, UMR 5128, Villeurbanne, France. Electronic address:
Carboxylic acids and aromatic compounds are essential building blocks and starting materials for the production of a wide range of fine chemicals and materials. Their recovery from kraft black liquor, an industrial effluent from pulp and paper mills, is a promising way to produce alternative bio-based chemicals. Reliable methods are needed to identify and quantify the molecules of interest in complex mixtures such as black liquors.
View Article and Find Full Text PDFSurg Pract Sci
March 2024
Surgery Department, Hospital Pedro Hispano, R. de Dr. Eduardo Torres, Matosinhos, Senhora da Hora 4464-513, Portugal.
Background: Totally implantable venous central access devices (TIVADs) can be implanted by open surgery or by direct puncture in the subclavian (ScV), internal jugular (IJV) or cephalic (CephV) veins.
Methods: A retrospective study was conducted in 201 patients. Thirty-day follow-up data was analyzed to compare the outcomes of different techniques and evaluation of risk factors.
Metabolomics
November 2024
Biosystems and Biomaterials Division, National Institute of Standards and Technology (NIST), 100 Bureau Dr. , Gaithersburg, MD, 20899, USA.
Introduction: Human metabolomics has made significant strides in understanding metabolic changes and their implications for human health, with promising applications in diagnostics and treatment, particularly regarding the gut microbiome. However, progress is hampered by issues with data comparability and reproducibility across studies, limiting the translation of these discoveries into practical applications.
Objectives: This study aims to evaluate the fit-for-purpose of a suite of human stool samples as potential candidate reference materials (RMs) and assess the state of the field regarding harmonizing gut metabolomics measurements.
Spectrochim Acta A Mol Biomol Spectrosc
February 2025
Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, China; Spallation Neutron Source Science Center, China Spallation Neutron Source, Dongguan 523803, China. Electronic address:
Nephrite, a historically significant material in Chinese jade culture, varies in elemental composition and spectroscopic properties based on its geographic origin due to differing mineralization environments. This study aims to address the limitations of traditional methods by employing a multi-technique approach that combines XRF mapping, fiber optic reflectance spectroscopy (FORS), near-infrared spectroscopy (NIR), and synchrotron-based X-ray absorption fine structure (XAFS) analysis, focusing on a comprehensive characterization of Fe to understand the properties of nephrite from various provenances. Our results reveal that while major elements like Si, Mg, and Ca are uniformly distributed, elements such as K, Mn, and Fe show significant variability, with Fe and Mn exhibiting nearly identical distribution patterns.
View Article and Find Full Text PDFMolecules
October 2024
Key Laboratory of Microbiological Metrology, Measurement & Bio-product Quality Security, State Administration for Market Regulation, College of Life Sciences, China Jiliang University, Hangzhou 310018, China.
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