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"It gets you high as a kite but not unsick": Characterizations of and responses to a changing local drug supply by people who use drugs in Rhode Island.
Int J Drug Policy
May 2024
Department of Emergency Medicine, Warren Alpert Medical School of Brown University, Providence, RI, USA.
Background: The North American overdose crisis has continued at unprecedented rates with more than 100,000 overdose deaths occurring in the United States (US) in 2022. Overdose deaths have increasingly been polysubstance-involved, with novel substances (e.g.
View Article and Find Full Text PDFThe Impact of Isolated Preoperative Cannabis Use on Outcomes Following Cervical Spinal Fusion: A Propensity Score-Matched Analysis.
Iowa Orthop J
December 2023
Department of Orthopaedic Surgery and Rehabilitation Medicine, The State University of New York Downstate Health Sciences University, Brooklyn, New York, USA.
Background: Cannabis is the most commonly used recreational drug in the USA. Studies evaluating cannabis use and its impact on outcomes following cervical spinal fusion (CF) are limited. This study sought to assess the impact of isolated (exclusive) cannabis use on postoperative outcomes following CF by analyzing outcomes like complications, readmissions, and revisions.
View Article and Find Full Text PDFThe impact of polysubstance use patterns on engagement of substance use disorder treatment among emergency department patients at high risk of opioid overdose.
Addict Behav Rep
December 2023
Brown University School of Public Health, Department of Epidemiology, 121 South Main Street, Providence, RI 02903, USA.
Background: Substance use patterns are diverse, and multiple substances are often involved in fatal and nonfatal overdoses. Additionally, polysubstance use is associated with greater difficulty accessing and remaining in substance use disorder (SUD) treatment. The aim of this study was to identify substance use patterns and determine their association with SUD treatment engagement among emergency department (ED) patients at risk of opioid overdose.
View Article and Find Full Text PDFReceipt of Prescription Psychostimulants and Stimulant-Involved Fatal Overdose: A Population-Based Case-Control Study.
Subst Use Misuse
June 2023
Brown University School of Public Health, Providence, Rhode Island, USA.
Rates of psychostimulant use, misuse, and hospitalization have increased markedly over the past decade. The objective of this study was to estimate the association between receipt of a psychostimulant prescription in the past year and fatal, unintentional psychostimulant-involved overdose. We conducted a population-based case-control study using linked, state-level databases from the Rhode Island Department of Health.
View Article and Find Full Text PDFPrenatal Substance Exposure: Associations with Neurodevelopment in Middle Childhood.
Am J Perinatol
May 2024
Women and Infants Hospital of Rhode Island, Providence, Rhode Island.
Objective: Single-substance exposure effects on neurodevelopmental outcomes, such as problem behavior and intelligence quotient (IQ), have been studied in children for decades. However, the long-term consequences of polysubstance exposure are poorly understood.
Study Design: Longitudinal neurodevelopmental data were gathered from cohorts across the United States through the Environmental Influences on Child Health Outcomes Program.
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