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Habitual consumption of high-fibre bread fortified with bean hulls increased plasma indole-3-propionic concentration and decreased putrescine and deoxycholic acid faecal concentrations in healthy volunteers. | LitMetric

AI Article Synopsis

  • *In a study with nine participants, those consuming bean hull rolls for three days saw significant changes in certain metabolites and gut health markers, especially increased levels of indole-3-propionic acid and decreased levels of putrescine.
  • *Despite the high fiber content in bean hull rolls, the bioavailability of beneficial plant metabolites was low, indicating a need for further processing to enhance their health benefits.

Article Abstract

Only 6 to 8 % of the UK adults meet the daily recommendation for dietary fibre. Fava bean processing lead to vast amounts of high-fibre by-products such as hulls. Bean hull fortified bread was formulated to increase and diversify dietary fibre while reducing waste. This study assessed the bean hull: suitability as a source of dietary fibre; the systemic and microbial metabolism of its components and postprandial events following bean hull bread rolls. Nine healthy participants (53·9 ± 16·7 years) were recruited for a randomised controlled crossover study attending two 3 days intervention sessions, involving the consumption of two bread rolls per day (control or bean hull rolls). Blood and faecal samples were collected before and after each session and analysed for systemic and microbial metabolites of bread roll components using targeted LC-MS/MS and GC analysis. Satiety, gut hormones, glucose, insulin and gastric emptying biomarkers were also measured. Two bean hull rolls provided over 85 % of the daily recommendation for dietary fibre; but despite being a rich source of plant metabolites ( = 0·04 . control bread), these had poor systemic bioavailability. Consumption of bean hull rolls for 3 days significantly increased plasma concentration of indole-3-propionic acid ( = 0·009) and decreased faecal concentration of putrescine ( = 0·035) and deoxycholic acid ( = 0·046). However, it had no effect on postprandial plasma gut hormones, bacterial composition and faecal short chain fatty acids amount. Therefore, bean hulls require further processing to improve their bioactives systemic availability and fibre fermentation.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10551484PMC
http://dx.doi.org/10.1017/S0007114523000491DOI Listing

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